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Research Article

Quercetin Inhibits Angiogenesis Mediated Human Prostate Tumor Growth by Targeting VEGFR- 2 Regulated AKT/mTOR/P70S6K Signaling Pathways

  • Poyil Pratheeshkumar,

    Affiliation: Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

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  • Amit Budhraja,

    Affiliation: Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

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  • Young-Ok Son,

    Affiliation: Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

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  • Xin Wang,

    Affiliation: Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

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  • Zhuo Zhang,

    Affiliation: Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

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  • Songze Ding,

    Affiliation: Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

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  • Lei Wang,

    Affiliation: Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

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  • Andrew Hitron,

    Affiliation: Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

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  • Jeong-Chae Lee,

    Affiliation: Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

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  • Mei Xu,

    Affiliation: Department of Internal Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

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  • Gang Chen,

    Affiliation: Department of Internal Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

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  • Jia Luo,

    Affiliation: Department of Internal Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

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  • Xianglin Shi mail

    xshi5@email.uky.edu

    Affiliation: Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

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  • Published: October 18, 2012
  • DOI: 10.1371/journal.pone.0047516

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