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Research Article

IRF1 and NF-kB Restore MHC Class I-Restricted Tumor Antigen Processing and Presentation to Cytotoxic T Cells in Aggressive Neuroblastoma

  • Silvia Lorenzi equal contributor,

    equal contributor Contributed equally to this work with: Silvia Lorenzi, Matteo Forloni

    Affiliation: Paediatric Haematology/Oncology Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

    X
  • Matteo Forloni equal contributor,

    equal contributor Contributed equally to this work with: Silvia Lorenzi, Matteo Forloni

    Affiliation: Paediatric Haematology/Oncology Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

    X
  • Loredana Cifaldi,

    Affiliation: Paediatric Haematology/Oncology Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

    X
  • Chiara Antonucci,

    Affiliation: Paediatric Haematology/Oncology Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

    X
  • Arianna Citti,

    Affiliation: Pathology Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

    X
  • Renata Boldrini,

    Affiliation: Pathology Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

    X
  • Marco Pezzullo,

    Affiliation: Paediatric Haematology/Oncology Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

    X
  • Aurora Castellano,

    Affiliation: Paediatric Haematology/Oncology Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

    X
  • Vincenzo Russo,

    Affiliation: Cancer Gene Therapy Unit, Scientific Institute San Raffaele, Milan, Italy

    X
  • Pierre van der Bruggen,

    Affiliation: Laboratory of Immunology CRS, Regina Elena National Cancer Institute, Rome, Italy

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  • Patrizio Giacomini,

    Affiliation: Ludwig Institute for Cancer Research and Université Catholique de Louvain, de Duve Institute, Brussels, Belgium

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  • Franco Locatelli,

    Affiliations: Paediatric Haematology/Oncology Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy, University of Pavia, Pavia, Italy

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  • Doriana Fruci mail

    fruci@opbg.net

    Affiliation: Paediatric Haematology/Oncology Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

    X
  • Published: October 05, 2012
  • DOI: 10.1371/journal.pone.0046928

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