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Research Article

Functional Polymorphisms of CHRNA3 Predict Risks of Chronic Obstructive Pulmonary Disease and Lung Cancer in Chinese

  • Lei Yang,

    Affiliation: School of Public Health, The Institute for Chemical Carcinogenesis, The State Key Lab of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China

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  • Fuman Qiu,

    Affiliation: School of Public Health, The Institute for Chemical Carcinogenesis, The State Key Lab of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China

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  • Xiaoxiao Lu,

    Affiliation: School of Public Health, The Institute for Chemical Carcinogenesis, The State Key Lab of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China

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  • Dongsheng Huang,

    Affiliations: School of Public Health, The Institute for Chemical Carcinogenesis, The State Key Lab of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China, Department of Respiratory Medicine, Guangzhou Chest Hospital, Guangzhou, Guangdong, China

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  • Guanpei Ma,

    Affiliation: School of Public Health, The Institute for Chemical Carcinogenesis, The State Key Lab of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China

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  • Yuan Guo,

    Affiliation: The third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China

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  • Min Hu,

    Affiliation: Soochow University Laboratory of Cancer Molecular Genetics, Medical College of Soochow University, Suzhou, China

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  • Yumin Zhou,

    Affiliation: Guangzhou Institute of Respiratory Diseases, The First Affiliated Hospital, The State Key Lab of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China

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  • Mingan Pan,

    Affiliation: Department of Respiratory Medicine, the third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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  • Yigang Tan,

    Affiliation: Department of Respiratory Medicine, Guangzhou Chest Hospital, Guangzhou, Guangdong, China

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  • Haibo Zhong,

    Affiliation: Department of Respiratory Medicine, Guangzhou Red Cross Hospital, Guangzhou, Guangdong, China

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  • Weidong Ji,

    Affiliation: School of Public Health, The Institute for Chemical Carcinogenesis, The State Key Lab of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China

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  • Qingyi Wei,

    Affiliation: Department of Epidemiology, The University of Texas M.D. Anderson Cancer Center, Houston, United States of America

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  • Pixin Ran,

    Affiliation: Guangzhou Institute of Respiratory Diseases, The First Affiliated Hospital, The State Key Lab of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China

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  • Nanshan Zhong,

    Affiliation: Guangzhou Institute of Respiratory Diseases, The First Affiliated Hospital, The State Key Lab of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China

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  • Yifeng Zhou,

    Affiliation: Soochow University Laboratory of Cancer Molecular Genetics, Medical College of Soochow University, Suzhou, China

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  • Jiachun Lu mail

    jcLu@gzhmc.edu.cn

    Affiliation: School of Public Health, The Institute for Chemical Carcinogenesis, The State Key Lab of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China

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  • Published: October 03, 2012
  • DOI: 10.1371/journal.pone.0046071

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