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Research Article

Loss of Expression and Function of SOCS3 Is an Early Event in HNSCC: Altered Subcellular Localization as a Possible Mechanism Involved in Proliferation, Migration and Invasion

  • Carlos Rossa Jr. mail,

    crossajr@foar.unesp.br

    Affiliation: Department of Diagnosis and Surgery-School of Dentistry at Araraquara-Universidade Estadual Paulista (UNESP), Araraquara, São Paulo, Brazil

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  • Gunhild Sommer,

    Affiliation: Department of Biochemistry and Molecular Biology, Medical University of South Carolina (MUSC), Charleston, South Carolina, United States of America

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  • Luis C. Spolidorio,

    Affiliation: Department of Physiology and Pathology-School of Dentistry at Araraquara-Universidade Estadual Paulista (UNESP), Araraquara, São Paulo, Brazil

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  • Steven A. Rosenzweig,

    Affiliation: Department of Pharmacology, Medical University of South Carolina (MUSC), Charleston, South Carolina, United States of America

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  • Dennis K. Watson,

    Affiliations: Department of Biochemistry and Molecular Biology, Medical University of South Carolina (MUSC), Charleston, South Carolina, United States of America, Department of Pathology and Laboratory Medicine, Medical University of South Carolina (MUSC), Charleston, South Carolina, United States of America

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  • Keith L. Kirkwood

    Affiliation: Department of Craniofacial Biology and Center for Oral Health, Medical University of South Carolina (MUSC), Charleston, South Carolina, United States of America

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  • Published: September 18, 2012
  • DOI: 10.1371/journal.pone.0045197

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