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Research Article

Measuring Cation Dependent DNA Polymerase Fidelity Landscapes by Deep Sequencing

  • Bradley Michael Zamft equal contributor,

    equal contributor Contributed equally to this work with: Bradley Michael Zamft, Adam H. Marblestone

    Affiliation: Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Adam H. Marblestone equal contributor,

    equal contributor Contributed equally to this work with: Bradley Michael Zamft, Adam H. Marblestone

    Affiliations: Biophysics Program, Harvard University, Boston, Massachusetts, United States of America, Wyss Institute, Harvard University, Boston, Massachusetts, United States of America

    X
  • Konrad Kording,

    Affiliations: Northwestern University, Departments of Physical Medicine and Rehabilitation, Physiology, and Applied Mathematics, Chicago, Illinois, United States of America, The Rehabilitation Institute of Chicago, Chicago, Illinois, United States of America

    X
  • Daniel Schmidt,

    Affiliations: Media Lab, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, McGovern Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

    X
  • Daniel Martin-Alarcon,

    Affiliations: Media Lab, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, McGovern Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

    X
  • Keith Tyo,

    Affiliation: Department of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois, United States of America

    X
  • Edward S. Boyden,

    Affiliations: Media Lab, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, McGovern Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

    X
  • George Church mail

    gchurch@genetics.med.harvard.edu

    Affiliations: Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Biophysics Program, Harvard University, Boston, Massachusetts, United States of America

    X
  • Published: August 22, 2012
  • DOI: 10.1371/journal.pone.0043876

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