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Research Article

δ-Catenin Is Genetically and Biologically Associated with Cortical Cataract and Future Alzheimer-Related Structural and Functional Brain Changes

  • Gyungah Jun mail,

    gyungah@bu.edu (GJ); farrer@bu.edu (LAF)

    Affiliations: Department of Medicine (Biomedical Genetics), Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Ophthalmology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Biostatistics, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

    X
  • Juliet A. Moncaster,

    Affiliation: Department of Psychiatry, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

    X
  • Carolina Koutras,

    Affiliation: Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada

    X
  • Sudha Seshadri,

    Affiliations: Department of Neurology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Framingham Heart Study, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

    X
  • Jacqueline Buros,

    Affiliation: Department of Medicine (Biomedical Genetics), Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

    X
  • Ann C. McKee,

    Affiliations: Department of Neurology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Pathology & Laboratory Medicine, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Boston University Alzheimer's Disease Center, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Geriatric Research Education Clinical Center, Bedford Veterans Administration Hospital, Bedford, Massachusetts, United States of America

    X
  • Georges Levesque,

    Affiliation: Neurosciences Research Centre-CHUL, Université Laval, Québec, Canada

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  • Philip A. Wolf,

    Affiliations: Department of Neurology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Epidemiology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Framingham Heart Study, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

    X
  • Peter St. George-Hyslop,

    Affiliations: Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom

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  • Lee E. Goldstein,

    Affiliations: Department of Psychiatry, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Neurology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Pathology & Laboratory Medicine, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Boston University Alzheimer's Disease Center, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

    X
  • Lindsay A. Farrer mail

    gyungah@bu.edu (GJ); farrer@bu.edu (LAF)

    Affiliations: Department of Medicine (Biomedical Genetics), Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Ophthalmology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Biostatistics, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Neurology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Epidemiology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Boston University Alzheimer's Disease Center, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

    X
  • Published: September 11, 2012
  • DOI: 10.1371/journal.pone.0043728

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