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Research Article

Plant Lectin Can Target Receptors Containing Sialic Acid, Exemplified by Podoplanin, to Inhibit Transformed Cell Growth and Migration

  • Jhon Alberto Ochoa-Alvarez equal contributor,

    equal contributor Contributed equally to this work with: Jhon Alberto Ochoa-Alvarez, Harini Krishnan

    Affiliations: Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America, Department of Molecular Biology, School of Osteopathic Medicine, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America

    X
  • Harini Krishnan equal contributor,

    equal contributor Contributed equally to this work with: Jhon Alberto Ochoa-Alvarez, Harini Krishnan

    Affiliations: Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America, Department of Molecular Biology, School of Osteopathic Medicine, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America

    X
  • Yongquan Shen,

    Affiliation: Department of Molecular Biology, School of Osteopathic Medicine, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America

    X
  • Nimish K. Acharya,

    Affiliations: Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America, New Jersey Institute for Successful Aging, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America

    X
  • Min Han,

    Affiliations: Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America, New Jersey Institute for Successful Aging, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America

    X
  • Dean E. McNulty,

    Affiliation: Proteomics and Biological Mass Spectrometry, Molecular Discovery Research, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America

    X
  • Hitoki Hasegawa,

    Affiliation: Division of Cancer Biology, School of Medicine, Nagoya University, Nagoya, Japan

    X
  • Toshinori Hyodo,

    Affiliation: Division of Cancer Biology, School of Medicine, Nagoya University, Nagoya, Japan

    X
  • Takeshi Senga,

    Affiliation: Division of Cancer Biology, School of Medicine, Nagoya University, Nagoya, Japan

    X
  • Jian-Guo Geng,

    Affiliation: Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, Michigan, United States of America

    X
  • Mary Kosciuk,

    Affiliation: New Jersey Institute for Successful Aging, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America

    X
  • Seung S. Shin,

    Affiliation: Department of Surgery, Cancer Institute of New Jersey, New Brunswick, New Jersey, United States of America

    X
  • James S. Goydos,

    Affiliation: Department of Surgery, Cancer Institute of New Jersey, New Brunswick, New Jersey, United States of America

    X
  • Dmitry Temiakov,

    Affiliations: Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America, Department of Cell Biology, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America

    X
  • Robert G. Nagele,

    Affiliations: Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America, New Jersey Institute for Successful Aging, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America

    X
  • Gary S. Goldberg mail

    gary.goldberg@umdnj.edu

    Affiliations: Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America, Department of Molecular Biology, School of Osteopathic Medicine, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, United States of America

    X
  • Published: July 23, 2012
  • DOI: 10.1371/journal.pone.0041845

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