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Open Access
Peer-reviewed
Research Article
A Gene Co-Expression Network in Whole Blood of Schizophrenia Patients Is Independent of Antipsychotic-Use and Enriched for Brain-Expressed Genes
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Simone de Jong,
Current address: Center for Neurobehavioral Genetics, University of California Los Angeles, Los Angeles, California, United States of America
Affiliations Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
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Marco P. M. Boks,
Affiliations Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands, Julius Centre for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
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Tova F. Fuller,
Affiliation Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America
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Eric Strengman,
Affiliations Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands, Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, University of California Los Angeles, Los Angeles, California, United States of America
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Esther Janson,
Affiliation Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
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Carolien G. F. de Kovel,
Affiliation Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
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Anil P. S. Ori,
Affiliation Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, University of California Los Angeles, Los Angeles, California, United States of America
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Nancy Vi,
Affiliation Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, University of California Los Angeles, Los Angeles, California, United States of America
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Flip Mulder,
Affiliation Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
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Jan Dirk Blom,
Affiliations Parnassia Bravo Group, The Hague, The Netherlands, Department of Psychiatry, University of Groningen, Groningen, The Netherlands
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Birte Glenthøj,
Affiliation Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Psychiatric University Center Glostrup, University of Copenhagen, Glostrup, Denmark
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Chris D. Schubart,
Affiliation Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
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Wiepke Cahn,
Affiliation Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
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René S. Kahn,
Affiliation Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
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Steve Horvath,
Affiliations Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America, Department of Biostatistics, School of Public Health, University of California Los Angeles, Los Angeles, California, United States of America
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Roel A. Ophoff
* E-mail: ROphoff@mednet.ucla.edu
Affiliations Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America, Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, University of California Los Angeles, Los Angeles, California, United States of America
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A Gene Co-Expression Network in Whole Blood of Schizophrenia Patients Is Independent of Antipsychotic-Use and Enriched for Brain-Expressed Genes
- Simone de Jong,
- Marco P. M. Boks,
- Tova F. Fuller,
- Eric Strengman,
- Esther Janson,
- Carolien G. F. de Kovel,
- Anil P. S. Ori,
- Nancy Vi,
- Flip Mulder,
- Jan Dirk Blom
- Published: June 27, 2012
- https://doi.org/10.1371/journal.pone.0039498