Urinary Copper Elevation in a Mouse Model of Wilson's Disease Is a Regulated Process to Specifically Decrease the Hepatic Copper Load

• Lawrence W. Gray,

  Affiliation Department of Physiology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States of America

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• Fangyu Peng,

  Affiliation Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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• Shannon A. Molloy,

  Affiliation Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois, United States of America

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• Venkata S. Pendyala,

  Affiliation Department of Physiology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States of America

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• Abigael Muchenditsi,

  Affiliation Department of Physiology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States of America

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• Otto Muzik,

  Affiliation Carman and Ann Adams Department of Pediatrics and Department of Radiology, Wayne State University, School of Medicine, Detroit, Michigan, United States of America

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• Jaekwon Lee,

  Affiliation Redox Biology Center, Department of Biochemistry, University of Nebraska, Lincoln, Nebraska, United States of America

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• Jack H. Kaplan,

  Affiliation Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois, United States of America

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• Svetlana Lutsenko

  * E-mail: lutsenko@jhmi.edu

  Affiliation Department of Physiology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States of America

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