Advertisement
Research Article

Iron Accumulation in Deep Cortical Layers Accounts for MRI Signal Abnormalities in ALS: Correlating 7 Tesla MRI and Pathology

  • Justin Y. Kwan mail,

    kwanjy@ninds.nih.gov

    Affiliation: National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Suh Young Jeong,

    Affiliation: Molecular Medicine Program, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Peter Van Gelderen,

    Affiliation: Advanced MRI Section, Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Han-Xiang Deng,

    Affiliation: Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

    X
  • Martha M. Quezado,

    Affiliation: National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Laura E. Danielian,

    Affiliation: National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • John A. Butman,

    Affiliation: Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Lingye Chen,

    Affiliation: National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Elham Bayat,

    Affiliation: Department of Neurology, George Washington University, Washington, D. C., United States of America

    X
  • James Russell,

    Affiliation: Department of Neurology, University of Maryland, Baltimore, Maryland, United States of America

    X
  • Teepu Siddique,

    Affiliation: Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

    X
  • Jeff H. Duyn,

    Affiliation: Advanced MRI Section, Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Tracey A. Rouault,

    Affiliation: Molecular Medicine Program, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Mary Kay Floeter

    Affiliation: National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Published: April 17, 2012
  • DOI: 10.1371/journal.pone.0035241

Reader Comments (0)

Post a new comment on this article