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Research Article

Tumor-Targeted Delivery of IL-2 by NKG2D Leads to Accumulation of Antigen-Specific CD8+ T Cells in the Tumor Loci and Enhanced Anti-Tumor Effects

  • Tae Heung Kang,

    Affiliation: Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Chih-Ping Mao,

    Affiliation: Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Liangmei He,

    Affiliation: Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Ya-Chea Tsai,

    Affiliation: Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Katherine Liu,

    Affiliation: Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Victor La,

    Affiliation: Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • T.-C. Wu,

    Affiliations: Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Oncology, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Obstetrics and Gynecology, Johns Hopkins University, Baltimore, Maryland, United States of America, Molecular Microbiology and Immunology, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Chien-Fu Hung mail

    chung2@jhmi.edu

    Affiliations: Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Oncology, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Published: April 11, 2012
  • DOI: 10.1371/journal.pone.0035141

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