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Research Article

High-Throughput Sequencing of mGluR Signaling Pathway Genes Reveals Enrichment of Rare Variants in Autism

  • Raymond J. Kelleher III equal contributor mail,

    equal contributor Contributed equally to this work with: Raymond J. Kelleher III, Ute Geigenmüller

    kelleher@helix.mgh.harvard.edu

    Affiliations: Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Program in Neuroscience, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Ute Geigenmüller equal contributor,

    equal contributor Contributed equally to this work with: Raymond J. Kelleher III, Ute Geigenmüller

    Affiliation: Correlagen Diagnostics, Inc., Waltham, Massachusetts, United States of America

    Current address: Channing Laboratory, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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  • Hayk Hovhannisyan,

    Affiliation: Correlagen Diagnostics, Inc., Waltham, Massachusetts, United States of America

    X
  • Edwin Trautman,

    Affiliation: Correlagen Diagnostics, Inc., Waltham, Massachusetts, United States of America

    X
  • Robert Pinard,

    Affiliation: Correlagen Diagnostics, Inc., Waltham, Massachusetts, United States of America

    X
  • Barbara Rathmell,

    Affiliation: Seaside Therapeutics, Cambridge, Massachusetts, United States of America

    X
  • Randall Carpenter,

    Affiliation: Seaside Therapeutics, Cambridge, Massachusetts, United States of America

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  • David Margulies

    Affiliation: Correlagen Diagnostics, Inc., Waltham, Massachusetts, United States of America

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  • Published: April 27, 2012
  • DOI: 10.1371/journal.pone.0035003

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