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Open Access
Peer-reviewed
Research Article
Identification of KIF3A as a Novel Candidate Gene for Childhood Asthma Using RNA Expression and Population Allelic Frequencies Differences
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Melinda Butsch Kovacic,
Affiliations Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America, Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Jocelyn M. Biagini Myers,
Affiliation Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Ning Wang,
Affiliation Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Lisa J. Martin,
Affiliation Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Mark Lindsey,
Affiliation Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Mark B. Ericksen,
Affiliation Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Hua He,
Affiliation Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Tia L. Patterson,
Affiliation Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Tesfaye M. Baye,
Affiliation Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Dara Torgerson,
Affiliation The Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, California, United States of America
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Lindsey A. Roth,
Affiliation The Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, California, United States of America
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Jayanta Gupta,
Affiliation Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Umasundari Sivaprasad,
Affiliation Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Aaron M. Gibson,
Affiliation Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Anna M. Tsoras,
Affiliation Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Donglei Hu,
Affiliations The Lung Biology Center, San Francisco General Hospital, San Francisco, California, United States of America, The Institute for Human Genetics, University of California San Francisco, San Francisco, California, United States of America
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Celeste Eng,
Affiliations The Lung Biology Center, San Francisco General Hospital, San Francisco, California, United States of America, The Institute for Human Genetics, University of California San Francisco, San Francisco, California, United States of America
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Rocío Chapela,
Affiliation Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico
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José R. Rodríguez-Santana,
Affiliation Centro de Neumología Pediátrica, CSP, San Juan, Puerto Rico, United States of America
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William Rodríguez-Cintrón,
Affiliation San Juan Veterans Affairs Medical Center, University of Puerto Rico School of Medicine, San Juan, Puerto Rico, United States of America
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Pedro C. Avila,
Affiliation Division of Allergy-Immunology, Northwestern University, Chicago, Illinois, United States of America
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Kenneth Beckman,
Affiliation Biomedical Genomics Center, University of Minnesota, Minneapolis, Minnesota, United States of America
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Max A. Seibold,
Affiliation Department of Medicine, National Jewish Health, Denver, Colorado, United States of America
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Chris Gignoux,
Affiliation The Institute for Human Genetics, University of California San Francisco, San Francisco, California, United States of America
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Salma M. Musaad,
Affiliation Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Weiguo Chen,
Affiliation Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Esteban González Burchard,
Affiliations The Lung Biology Center, San Francisco General Hospital, San Francisco, California, United States of America, The Institute for Human Genetics, University of California San Francisco, San Francisco, California, United States of America, The Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, California, United States of America
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Gurjit K. Khurana Hershey
* E-mail: gurjit.hershey @cchmc.org
Affiliation Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
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Identification of KIF3A as a Novel Candidate Gene for Childhood Asthma Using RNA Expression and Population Allelic Frequencies Differences
- Melinda Butsch Kovacic,
- Jocelyn M. Biagini Myers,
- Ning Wang,
- Lisa J. Martin,
- Mark Lindsey,
- Mark B. Ericksen,
- Hua He,
- Tia L. Patterson,
- Tesfaye M. Baye,
- Dara Torgerson
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- Published: August 30, 2011
- https://doi.org/10.1371/journal.pone.0023714