Live-Cell Microscopy Reveals Small Molecule Inhibitor Effects on MAPK Pathway Dynamics

Open Access

Peer-reviewed

Research Article

Daniel J. Anderson ,

* E-mail: anderson.daniel@gene.com

Affiliation Department of Cell Regulation, Genentech, Inc., South San Francisco, California, United States of America
⨯
Jenni K. Durieux,

Affiliation Department of Cell Regulation, Genentech, Inc., South San Francisco, California, United States of America
⨯
Kyung Song,

Affiliation Department of Cancer Signaling, Genentech, Inc., South San Francisco, California, United States of America
⨯
Ryan Alvarado,

Affiliation Department of Cancer Signaling, Genentech, Inc., South San Francisco, California, United States of America
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Peter K. Jackson,

Affiliation Department of Cell Regulation, Genentech, Inc., South San Francisco, California, United States of America
⨯
Georgia Hatzivassiliou,

Affiliation Department of Cancer Signaling, Genentech, Inc., South San Francisco, California, United States of America
⨯
Mary J. C. Ludlam

Affiliation Department of Cell Regulation, Genentech, Inc., South San Francisco, California, United States of America
⨯

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HEK 293 cells
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MAPK signaling cascades
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Transfection
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Priming (psychology)
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293T cells
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Image analysis
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Signal inhibition
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Small molecules
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