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Open Access
Peer-reviewed
Research Article
Metabolomic Profiling Reveals a Role for Androgen in Activating Amino Acid Metabolism and Methylation in Prostate Cancer Cells
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Nagireddy Putluri,
Current address: Department of Cellular and Molecular Biology, Verna and Marrs McLean Department of Biochemistry and Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, Texas, United States of America
Affiliations Cancer Center, Medical College of Georgia, Augusta, Georgia, United States of America, Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta, Georgia, United States of America
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Ali Shojaie,
Affiliation Department of Statistics, University of Michigan, Ann Arbor, Michigan, United States of America
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Vihas T. Vasu,
Affiliations Cancer Center, Medical College of Georgia, Augusta, Georgia, United States of America, Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta, Georgia, United States of America
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Srilatha Nalluri,
Affiliations Cancer Center, Medical College of Georgia, Augusta, Georgia, United States of America, Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta, Georgia, United States of America
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Shaiju K. Vareed,
Current address: Department of Cellular and Molecular Biology, Verna and Marrs McLean Department of Biochemistry and Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, Texas, United States of America
Affiliations Cancer Center, Medical College of Georgia, Augusta, Georgia, United States of America, Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta, Georgia, United States of America
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Vasanta Putluri,
Current address: Department of Cellular and Molecular Biology, Verna and Marrs McLean Department of Biochemistry and Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, Texas, United States of America
Affiliations Cancer Center, Medical College of Georgia, Augusta, Georgia, United States of America, Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta, Georgia, United States of America
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Anuradha Vivekanandan-Giri,
Affiliation Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America
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Jeman Byun,
Affiliation Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America
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Subramaniam Pennathur,
Affiliation Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America
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Theodore R. Sana,
Affiliation Metabolomics Laboratory Application Group, Agilent Technologies, Santa Clara, California, United States of America
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Steven M. Fischer,
Affiliation Metabolomics Laboratory Application Group, Agilent Technologies, Santa Clara, California, United States of America
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Ganesh S. Palapattu,
Affiliation Department of Urology, The Methodist Hospital, Houston, Texas, Unites States of America
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Chad J. Creighton,
Affiliation Dan. L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, United States of America
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George Michailidis,
Affiliation Department of Statistics, University of Michigan, Ann Arbor, Michigan, United States of America
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Arun Sreekumar
* E-mail: sreekuma@bcm.edu
Current address: Department of Cellular and Molecular Biology, Verna and Marrs McLean Department of Biochemistry and Alkek Center for Molecular Discovery, Baylor College of Medicine, Houston, Texas, United States of America
Affiliations Cancer Center, Medical College of Georgia, Augusta, Georgia, United States of America, Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta, Georgia, United States of America, Department of Urology, Medical College of Georgia, Augusta, Georgia, United States of America, Department of Surgery, Medical College of Georgia, Augusta, Georgia, United States of America
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Metabolomic Profiling Reveals a Role for Androgen in Activating Amino Acid Metabolism and Methylation in Prostate Cancer Cells
- Nagireddy Putluri,
- Ali Shojaie,
- Vihas T. Vasu,
- Srilatha Nalluri,
- Shaiju K. Vareed,
- Vasanta Putluri,
- Anuradha Vivekanandan-Giri,
- Jeman Byun,
- Subramaniam Pennathur,
- Theodore R. Sana
- Published: July 18, 2011
- https://doi.org/10.1371/journal.pone.0021417