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Research Article

Mitochondrial Ceramide-Rich Macrodomains Functionalize Bax upon Irradiation

  • Hyunmi Lee,

    Affiliation: Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Jimmy A. Rotolo,

    Affiliation: Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Judith Mesicek,

    Affiliation: Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Tuula Penate-Medina,

    Affiliation: Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Andreas Rimner,

    Affiliation: Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Wen-Chieh Liao,

    Affiliation: Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Xianglei Yin,

    Affiliation: Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Govind Ragupathi,

    Affiliation: Laboratory of Tumor Vaccinology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Desiree Ehleiter,

    Affiliation: Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Erich Gulbins,

    Affiliation: Department of Molecular Biology, University of Duisburg-Essen, Essen, Germany

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  • Dayong Zhai,

    Affiliation: Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

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  • John C. Reed,

    Affiliation: Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

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  • Adriana Haimovitz-Friedman,

    Affiliation: Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Zvi Fuks,

    Affiliation: Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Richard Kolesnick mail

    r-kolesnick@ski.mskcc.org

    Affiliation: Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Published: June 13, 2011
  • DOI: 10.1371/journal.pone.0019783

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