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Research Article

Stalking the Fourth Domain in Metagenomic Data: Searching for, Discovering, and Interpreting Novel, Deep Branches in Marker Gene Phylogenetic Trees

  • Dongying Wu,

    Affiliation: Department of Evolution and Ecology, Department of Medical Microbiology and Immunology, University of California Davis Genome Center, University of California Davis, Davis, California, United States of America

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  • Martin Wu,

    Affiliations: Department of Evolution and Ecology, Department of Medical Microbiology and Immunology, University of California Davis Genome Center, University of California Davis, Davis, California, United States of America, University of Virginia, Charlottesville, Virginia, United States of America

    X
  • Aaron Halpern,

    Affiliations: The J. Craig Venter Institute, Rockville, Maryland, United States of America, The J. Craig Venter Institute, La Jolla, California, United States of America

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  • Douglas B. Rusch,

    Affiliations: The J. Craig Venter Institute, Rockville, Maryland, United States of America, The J. Craig Venter Institute, La Jolla, California, United States of America

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  • Shibu Yooseph,

    Affiliations: The J. Craig Venter Institute, Rockville, Maryland, United States of America, The J. Craig Venter Institute, La Jolla, California, United States of America

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  • Marvin Frazier,

    Affiliations: The J. Craig Venter Institute, Rockville, Maryland, United States of America, The J. Craig Venter Institute, La Jolla, California, United States of America

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  • J. Craig Venter,

    Affiliations: The J. Craig Venter Institute, Rockville, Maryland, United States of America, The J. Craig Venter Institute, La Jolla, California, United States of America

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  • Jonathan A. Eisen mail

    jaeisen@ucdavis.edu

    Affiliation: Department of Evolution and Ecology, Department of Medical Microbiology and Immunology, University of California Davis Genome Center, University of California Davis, Davis, California, United States of America

    X
  • Published: March 18, 2011
  • DOI: 10.1371/journal.pone.0018011

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