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Research Article

Autism and Increased Paternal Age Related Changes in Global Levels of Gene Expression Regulation

  • Mark D. Alter mail,

    markalter1968@gmail.com

    Affiliation: Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Rutwik Kharkar,

    Affiliation: Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Keri E. Ramsey,

    Affiliation: Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona, United States of America

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  • David W. Craig,

    Affiliation: Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona, United States of America

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  • Raun D. Melmed,

    Affiliation: Southwest Autism Research and Resource Center, Phoenix, Arizona, United States of America

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  • Theresa A. Grebe,

    Affiliation: Southwest Autism Research and Resource Center, Phoenix, Arizona, United States of America

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  • R. Curtis Bay,

    Affiliation: Southwest Autism Research and Resource Center, Phoenix, Arizona, United States of America

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  • Sharman Ober-Reynolds,

    Affiliation: Southwest Autism Research and Resource Center, Phoenix, Arizona, United States of America

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  • Janet Kirwan,

    Affiliation: Southwest Autism Research and Resource Center, Phoenix, Arizona, United States of America

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  • Josh J. Jones,

    Affiliation: Southwest Autism Research and Resource Center, Phoenix, Arizona, United States of America

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  • J. Blake Turner,

    Affiliation: Division of Child and Adolescent Psychiatry, Department of Psychiatry, Columbia University, New York, New York, United States of America

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  • Rene Hen,

    Affiliation: Departments of Psychiatry and Neuroscience, Columbia University, New York, New York, United States of America

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  • Dietrich A. Stephan

    Affiliation: Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona, United States of America

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  • Published: February 17, 2011
  • DOI: 10.1371/journal.pone.0016715

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