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Research Article

The Physiological Link between Metabolic Rate Depression and Tau Phosphorylation in Mammalian Hibernation

  • Jens T. Stieler mail,

    jens.stieler@gmx.de

    Affiliations: Department of Molecular and Cellular Mechanisms of Neurodegeneration, Paul Flechsig Institute of Brain Research, University of Leipzig, Leipzig, Germany, Institute of Medical Microbiology and Hygiene, University Medical Centre of the Johannes Gutenberg-University Mainz, Mainz, Germany

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  • Torsten Bullmann,

    Affiliation: Department of Molecular and Cellular Mechanisms of Neurodegeneration, Paul Flechsig Institute of Brain Research, University of Leipzig, Leipzig, Germany

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  • Franziska Kohl,

    Affiliation: Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska, United States of America

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  • Øivind Tøien,

    Affiliation: Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska, United States of America

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  • Martina K. Brückner,

    Affiliation: Department of Molecular and Cellular Mechanisms of Neurodegeneration, Paul Flechsig Institute of Brain Research, University of Leipzig, Leipzig, Germany

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  • Wolfgang Härtig,

    Affiliation: Department of Pathophysiology of Neuroglia, Paul Flechsig Institute of Brain Research, University of Leipzig, Leipzig, Germany

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  • Brian M. Barnes,

    Affiliation: Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska, United States of America

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  • Thomas Arendt

    Affiliation: Department of Molecular and Cellular Mechanisms of Neurodegeneration, Paul Flechsig Institute of Brain Research, University of Leipzig, Leipzig, Germany

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  • Published: January 18, 2011
  • DOI: 10.1371/journal.pone.0014530

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