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Open Access
Peer-reviewed
Research Article
Amino-Acid Co-Variation in HIV-1 Gag Subtype C: HLA-Mediated Selection Pressure and Compensatory Dynamics
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Morgane Rolland ,
* E-mail: mrolland@u.washington.edu
Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America
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Jonathan M. Carlson,
Affiliation Microsoft Research, Redmond, Washington, United States of America
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Siriphan Manocheewa,
Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America
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J. Victor Swain,
Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America
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Erinn Lanxon-Cookson,
Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America
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Wenjie Deng,
Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America
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Christine M. Rousseau,
Current address: Bill and Melinda Gates Foundation, Seattle, Washington, United States of America
Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America
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Dana N. Raugi,
Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America
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Gerald H. Learn,
Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America
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Brandon S. Maust,
Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America
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Hoosen Coovadia,
Affiliation HIV Pathogenesis Program, Nelson Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
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Thumbi Ndung'u,
Affiliation HIV Pathogenesis Program, Nelson Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
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Philip J. R. Goulder,
Affiliations HIV Pathogenesis Program, Nelson Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa, Department of Pediatrics, Nuffield Department of Medicine, Oxford University, Oxford, United Kingdom, Ragon Institute of MGH, MIT and Harvard, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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Bruce D. Walker,
Affiliations Ragon Institute of MGH, MIT and Harvard, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America
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Christian Brander,
Current address: Laboratori de Retrovirologia, Fundació irsiCaixa, Barcelona, Spain
Affiliation Ragon Institute of MGH, MIT and Harvard, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
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David E. Heckerman,
Affiliation Microsoft Research, Redmond, Washington, United States of America
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James I. Mullins
Affiliations Department of Microbiology, University of Washington, Seattle, Washington, United States of America, Department of Medicine, University of Washington, Seattle, Washington, United States of America
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Amino-Acid Co-Variation in HIV-1 Gag Subtype C: HLA-Mediated Selection Pressure and Compensatory Dynamics
- Morgane Rolland,
- Jonathan M. Carlson,
- Siriphan Manocheewa,
- J. Victor Swain,
- Erinn Lanxon-Cookson,
- Wenjie Deng,
- Christine M. Rousseau,
- Dana N. Raugi,
- Gerald H. Learn,
- Brandon S. Maust
- Published: September 1, 2010
- https://doi.org/10.1371/journal.pone.0012463