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Research Article

The Mechanism of Release of P-TEFb and HEXIM1 from the 7SK snRNP by Viral and Cellular Activators Includes a Conformational Change in 7SK

  • Brian J. Krueger,

    Affiliation: Molecular and Cellular Biology Program, University of Iowa, Iowa City, Iowa, United States of America

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  • Katayoun Varzavand,

    Affiliation: Biochemistry Department, University of Iowa, Iowa City, Iowa, United States of America

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  • Jeffrey J. Cooper,

    Affiliation: Biochemistry Department, University of Iowa, Iowa City, Iowa, United States of America

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  • David H. Price mail

    david-price@uiowa.edu

    Affiliations: Molecular and Cellular Biology Program, University of Iowa, Iowa City, Iowa, United States of America, Biochemistry Department, University of Iowa, Iowa City, Iowa, United States of America

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  • Published: August 23, 2010
  • DOI: 10.1371/journal.pone.0012335

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