Mesenchymal Stem Cells Promote Mammosphere Formation and Decrease E-Cadherin in Normal and Malignant Breast Cells

Ann H. Klopp; Lara Lacerda; Anshul Gupta; Bisrat G. Debeb; Travis Solley; Li Li; Erika Spaeth; Wei Xu; Xiaomei Zhang; Michael T. Lewis; James M. Reuben; Savitri Krishnamurthy; Mauro Ferrari; Rogério Gaspar; Thomas A. Buchholz; Massimo Cristofanilli; Frank Marini; Michael Andreeff; Wendy A. Woodward

doi:10.1371/journal.pone.0012180

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Peer-reviewed

Research Article

Mesenchymal Stem Cells Promote Mammosphere Formation and Decrease E-Cadherin in Normal and Malignant Breast Cells

Ann H. Klopp ,

Contributed equally to this work with: Ann H. Klopp, Lara Lacerda

Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Lara Lacerda ,

Contributed equally to this work with: Ann H. Klopp, Lara Lacerda

Affiliations Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America, iMed.UL, Faculdade de Farmácia, Universidade de Lisboa, Lisbon, Portugal, Department of NanoMedicine and Biomedical Engineering, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America
⨯
Anshul Gupta,

Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Bisrat G. Debeb,

Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Travis Solley,

Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Li Li,

Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Erika Spaeth,

Affiliation Department of Stem Cell Transplant and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Wei Xu,

Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Xiaomei Zhang,

Affiliation Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Michael T. Lewis,

Affiliation Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas, United States of America
⨯
James M. Reuben,

Affiliation Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Savitri Krishnamurthy,

Affiliation Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Mauro Ferrari,

Affiliation Department of NanoMedicine and Biomedical Engineering, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America
⨯
Rogério Gaspar,

Affiliation iMed.UL, Faculdade de Farmácia, Universidade de Lisboa, Lisbon, Portugal
⨯
Thomas A. Buchholz,

Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Massimo Cristofanilli,

Affiliation Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Frank Marini,

Affiliation Department of Stem Cell Transplant and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Michael Andreeff,

Affiliation Department of Stem Cell Transplant and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
[ ... ],
Wendy A. Woodward

* E-mail: wwoodward@mdanderson.org

Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
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Mesenchymal Stem Cells Promote Mammosphere Formation and Decrease E-Cadherin in Normal and Malignant Breast Cells

Ann H. Klopp,
Lara Lacerda,
Anshul Gupta,
Bisrat G. Debeb,
Travis Solley,
Li Li,
Erika Spaeth,
Wei Xu,
Xiaomei Zhang,
Michael T. Lewis

Published: August 16, 2010
https://doi.org/10.1371/journal.pone.0012180

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08 Dec 2010
21:57 GMT
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grammatical error Posted by bcostantino on 08 Dec 2010 at 21:57 GMT

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Mesenchymal stem cells
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Breast cancer
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Cancers and neoplasms
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