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Research Article

Identification of a Novel Topoisomerase Inhibitor Effective in Cells Overexpressing Drug Efflux Transporters

  • Walid Fayad,

    Affiliation: Department of Oncology and Pathology, Karolinska Institute and Hospital, Stockholm, Sweden

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  • Mårten Fryknäs,

    Affiliation: Department of Medical Sciences, Division of Clinical Pharmacology, University Hospital, Uppsala University, Uppsala, Sweden

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  • Slavica Brnjic,

    Affiliation: Department of Oncology and Pathology, Karolinska Institute and Hospital, Stockholm, Sweden

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  • Maria Hägg Olofsson,

    Affiliation: Department of Oncology and Pathology, Karolinska Institute and Hospital, Stockholm, Sweden

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  • Rolf Larsson,

    Affiliation: Department of Medical Sciences, Division of Clinical Pharmacology, University Hospital, Uppsala University, Uppsala, Sweden

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  • Stig Linder mail

    Stig.Linder@ki.se

    Affiliation: Department of Oncology and Pathology, Karolinska Institute and Hospital, Stockholm, Sweden

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  • Published: October 02, 2009
  • DOI: 10.1371/journal.pone.0007238

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