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Research Article

Selective and Irreversible Inhibitors of Mosquito Acetylcholinesterases for Controlling Malaria and Other Mosquito-Borne Diseases

  • Yuan-Ping Pang mail,

    pang@mayo.edu (YPP); fredrik.ekstrom@foi.se (FE); brimijoi@mayo.edu (SB)

    Affiliation: Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Fredrik Ekström mail,

    pang@mayo.edu (YPP); fredrik.ekstrom@foi.se (FE); brimijoi@mayo.edu (SB)

    Affiliation: Swedish Defence Research Agency, CBRN Defence and Security, Umeå, Sweden

    X
  • Gregory A. Polsinelli,

    Affiliation: Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Yang Gao,

    Affiliation: Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Sandeep Rana,

    Affiliation: Department of Chemistry, Kansas State University, Manhattan, Kansas, United States of America

    X
  • Duy H. Hua,

    Affiliation: Department of Chemistry, Kansas State University, Manhattan, Kansas, United States of America

    X
  • Björn Andersson,

    Affiliation: Swedish Defence Research Agency, CBRN Defence and Security, Umeå, Sweden

    X
  • Per Ola Andersson,

    Affiliation: Swedish Defence Research Agency, CBRN Defence and Security, Umeå, Sweden

    X
  • Lei Peng,

    Affiliation: Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Sanjay K. Singh,

    Affiliation: Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America

    Current address: Department of Chemistry, University of Louisville, Louisville, Kentucky, United States of America

    X
  • Rajesh K. Mishra,

    Affiliation: Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Kun Yan Zhu,

    Affiliation: Department of Entomology, Kansas State University, Manhattan, Kansas, United States of America

    X
  • Ann M. Fallon,

    Affiliation: Department of Entomology, University of Minnesota, Saint Paul, Minnesota, United States of America

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  • David W. Ragsdale,

    Affiliation: Department of Entomology, University of Minnesota, Saint Paul, Minnesota, United States of America

    X
  • Stephen Brimijoin mail

    pang@mayo.edu (YPP); fredrik.ekstrom@foi.se (FE); brimijoi@mayo.edu (SB)

    Affiliation: Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Published: August 28, 2009
  • DOI: 10.1371/journal.pone.0006851

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