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Research Article

Identification of 2-Aminothiazole-4-Carboxylate Derivatives Active against Mycobacterium tuberculosis H37Rv and the β-Ketoacyl-ACP Synthase mtFabH

  • Qosay Al-Balas,

    Affiliation: Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom

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  • Nahoum G. Anthony,

    Affiliation: Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom

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  • Bilal Al-Jaidi,

    Affiliation: Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom

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  • Amani Alnimr,

    Affiliation: Department of Infection, University College London, London, United Kingdom

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  • Grainne Abbott,

    Affiliation: Strathclyde Innovations in Drug Research, Glasgow, United Kingdom

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  • Alistair K. Brown,

    Affiliation: School of Biosciences, University of Birmingham, Edgebaston, Birmingham, United Kingdom

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  • Rebecca C. Taylor,

    Affiliation: School of Biosciences, University of Birmingham, Edgebaston, Birmingham, United Kingdom

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  • Gurdyal S. Besra,

    Affiliation: School of Biosciences, University of Birmingham, Edgebaston, Birmingham, United Kingdom

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  • Timothy D. McHugh,

    Affiliation: Department of Infection, University College London, London, United Kingdom

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  • Stephen H. Gillespie,

    Affiliation: Department of Infection, University College London, London, United Kingdom

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  • Blair F. Johnston,

    Affiliation: Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom

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  • Simon P. Mackay,

    Affiliation: Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom

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  • Geoffrey D. Coxon mail

    geoff.coxon@strath.ac.uk

    Affiliation: Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom

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  • Published: May 19, 2009
  • DOI: 10.1371/journal.pone.0005617

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