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Research Article

Duplication and Diversification of the Hypoxia-Inducible IGFBP-1 Gene in Zebrafish

  • Hiroyasu Kamei,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Ling Lu,

    Affiliation: Laboratory of Molecular Medicine, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China

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  • Shuang Jiao,

    Affiliation: Laboratory of Molecular Medicine, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China

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  • Yun Li,

    Affiliation: Laboratory of Molecular Medicine, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China

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  • Claus Gyrup,

    Affiliation: Department of Molecular Biology, University of Aarhus, Aarhus C, Denmark

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  • Lisbeth S. Laursen,

    Affiliation: Department of Molecular Biology, University of Aarhus, Aarhus C, Denmark

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  • Claus Oxvig,

    Affiliation: Department of Molecular Biology, University of Aarhus, Aarhus C, Denmark

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  • Jianfeng Zhou,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Cunming Duan mail

    cduan@umich.edu

    Affiliations: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America, Laboratory of Molecular Medicine, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China

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  • Published: August 28, 2008
  • DOI: 10.1371/journal.pone.0003091

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