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Research Article

Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process

  • Wolfgang Wagner mail,

    wolfgang_wagner@med.uni-heidelberg.de

    Affiliations: Department of Medicine V, University of Heidelberg, Heidelberg, Germany, Department of Physiology and Pathophysiology, University of Heidelberg, Heidelberg, Germany

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  • Patrick Horn,

    Affiliation: Department of Medicine V, University of Heidelberg, Heidelberg, Germany

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  • Mirco Castoldi,

    Affiliation: Department of Pediatric Oncology, Hematology and Immunology, University of Heidelberg, Heidelberg, Germany

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  • Anke Diehlmann,

    Affiliation: Department of Medicine V, University of Heidelberg, Heidelberg, Germany

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  • Simone Bork,

    Affiliations: Department of Medicine V, University of Heidelberg, Heidelberg, Germany, Heidelberg Academy of Sciences and Humanities, Heidelberg, Germany

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  • Rainer Saffrich,

    Affiliation: Department of Medicine V, University of Heidelberg, Heidelberg, Germany

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  • Vladimir Benes,

    Affiliation: Genomics Core Facility, European Molecular Biology Laboratory, Heidelberg, Germany

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  • Jonathon Blake,

    Affiliation: Genomics Core Facility, European Molecular Biology Laboratory, Heidelberg, Germany

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  • Stefan Pfister,

    Affiliation: Department of Pediatric Oncology, Hematology and Immunology, University of Heidelberg, Heidelberg, Germany

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  • Volker Eckstein,

    Affiliation: Department of Medicine V, University of Heidelberg, Heidelberg, Germany

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  • Anthony D. Ho

    Affiliation: Department of Medicine V, University of Heidelberg, Heidelberg, Germany

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  • Published: May 21, 2008
  • DOI: 10.1371/journal.pone.0002213

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