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Research Article

The Mutant Form of Lamin A that Causes Hutchinson-Gilford Progeria Is a Biomarker of Cellular Aging in Human Skin

  • Dayle McClintock,

    Affiliation: Department of Dermatology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

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  • Desiree Ratner,

    Affiliation: Department of Dermatology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

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  • Meepa Lokuge,

    Affiliation: Department of Dermatology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

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  • David M. Owens,

    Affiliations: Department of Dermatology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America, Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

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  • Leslie B. Gordon,

    Affiliation: Department of BioMed Pediatrics, Brown University, Providence, Rhode Island, United States of America

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  • Francis S. Collins,

    Affiliation: Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Karima Djabali mail

    To whom correspondence should be addressed. E-mail: kd206@columbia.edu

    Affiliation: Department of Dermatology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

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  • Published: December 05, 2007
  • DOI: 10.1371/journal.pone.0001269

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