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Research Article

Tracking Virus-Specific CD4+ T Cells during and after Acute Hepatitis C Virus Infection

  • Michaela Lucas equal contributor,

    equal contributor Contributed equally to this work with: Michaela Lucas, Axel Ulsenheimer

    Affiliations: Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom, Centre for Clinical Immunology and Biomedical Statistics, Royal Perth Hospital and Murdoch University, Perth, Australia

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  • Axel Ulsenheimer equal contributor,

    equal contributor Contributed equally to this work with: Michaela Lucas, Axel Ulsenheimer

    Affiliation: Medical Department II and Institute for Immunology, Ludwig-Maximilians-University Munich, Munich, Germany

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  • Katja Pfafferot,

    Affiliation: Centre for Clinical Immunology and Biomedical Statistics, Royal Perth Hospital and Murdoch University, Perth, Australia

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  • Malte H.J. Heeg,

    Affiliation: Medical Department II and Institute for Immunology, Ludwig-Maximilians-University Munich, Munich, Germany

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  • Silvana Gaudieri,

    Affiliations: Centre for Clinical Immunology and Biomedical Statistics, Royal Perth Hospital and Murdoch University, Perth, Australia, Centre for Forensic Science, School of Anatomy and Human Biology, University of Western Australia, Nedlands, Australia

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  • Norbert Grüner,

    Affiliation: Medical Department II and Institute for Immunology, Ludwig-Maximilians-University Munich, Munich, Germany

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  • Andri Rauch,

    Affiliations: Centre for Clinical Immunology and Biomedical Statistics, Royal Perth Hospital and Murdoch University, Perth, Australia, Division of Infectious Diseases, University Hospital, Berne, Switzerland

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  • J. Tilman Gerlach,

    Affiliation: Medical Department II and Institute for Immunology, Ludwig-Maximilians-University Munich, Munich, Germany

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  • Maria-Christina Jung,

    Affiliation: Medical Department II and Institute for Immunology, Ludwig-Maximilians-University Munich, Munich, Germany

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  • Reinhart Zachoval,

    Affiliation: Medical Department II and Institute for Immunology, Ludwig-Maximilians-University Munich, Munich, Germany

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  • Gerd R. Pape,

    Affiliation: Medical Department II and Institute for Immunology, Ludwig-Maximilians-University Munich, Munich, Germany

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  • Winfried Schraut,

    Affiliation: Medical Department II and Institute for Immunology, Ludwig-Maximilians-University Munich, Munich, Germany

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  • Teresa Santantonio,

    Affiliation: Clinica delle Malattie Infettive, University of Bari, Bari, Italy

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  • Hans Nitschko,

    Affiliation: Max von Pettenkofer-Institute, Department of Virology, Ludwig-Maximilians-University Munich, Munich, Germany

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  • Martin Obermeier,

    Affiliation: Max von Pettenkofer-Institute, Department of Virology, Ludwig-Maximilians-University Munich, Munich, Germany

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  • Rodney Phillips,

    Affiliation: Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom

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  • Thomas J. Scriba,

    Affiliation: Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom

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  • Nasser Semmo,

    Affiliation: Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom

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  • Cheryl Day,

    Affiliation: Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom

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  • Jonathan N. Weber,

    Affiliation: Department of Medicine, Imperial College, St. Mary's Hospital, London, United Kingdom

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  • Sarah Fidler,

    Affiliation: Department of Medicine, Imperial College, St. Mary's Hospital, London, United Kingdom

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  • Robert Thimme,

    Affiliation: Albert-Ludwigs-Universität, Freiburg, Germany

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  • Anita Haberstroh,

    Affiliation: Albert-Ludwigs-Universität, Freiburg, Germany

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  • Thomas F. Baumert,

    Affiliation: Inserm Unité 748, Université Louis Pasteur, Strasbourg, France

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  • Paul Klenerman,

    Affiliation: Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom

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  • Helmut M. Diepolder mail

    To whom correspondence should be addressed. E-mail: hdiepold@med.uni-muenchen.de

    Affiliation: Medical Department II and Institute for Immunology, Ludwig-Maximilians-University Munich, Munich, Germany

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  • Published: July 25, 2007
  • DOI: 10.1371/journal.pone.0000649

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