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Research Article

A Novel Semi-Supervised Methodology for Extracting Tumor Type-Specific MRS Sources in Human Brain Data

  • Sandra Ortega-Martorell,

    Affiliation: Department of Mathematics and Statistics, Liverpool John Moores University, Liverpool, United Kingdom

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  • Héctor Ruiz,

    Affiliation: Department of Mathematics and Statistics, Liverpool John Moores University, Liverpool, United Kingdom

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  • Alfredo Vellido,

    Affiliation: Department of Computer Languages and Systems, Universitat Politècnica de Catalunya - BarcelonaTech, Barcelona, Spain

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  • Iván Olier,

    Affiliation: Institute of Population Health, The University of Manchester, Manchester, United Kingdom

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  • Enrique Romero,

    Affiliation: Department of Computer Languages and Systems, Universitat Politècnica de Catalunya - BarcelonaTech, Barcelona, Spain

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  • Margarida Julià-Sapé,

    Affiliations: Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Cerdanyola del Vallès, Spain, Departament de Bioquímica i Biología Molecular, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain, Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain

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  • José D. Martín,

    Affiliation: Departamento de Ingeniería Electrónica, Universidad de Valencia, Burjassot, Spain

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  • Ian H. Jarman,

    Affiliation: Department of Mathematics and Statistics, Liverpool John Moores University, Liverpool, United Kingdom

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  • Carles Arús,

    Affiliations: Departament de Bioquímica i Biología Molecular, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain, Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Cerdanyola del Vallès, Spain, Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain

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  • Paulo J. G. Lisboa mail

    P.J.Lisboa@ljmu.ac.uk

    Affiliation: Department of Mathematics and Statistics, Liverpool John Moores University, Liverpool, United Kingdom

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  • Published: December 23, 2013
  • DOI: 10.1371/journal.pone.0083773

About the Authors

Sandra Ortega-Martorell, Héctor Ruiz, Ian H. Jarman, Paulo J. G. Lisboa
Department of Mathematics and Statistics, Liverpool John Moores University, Liverpool, United Kingdom
Alfredo Vellido, Enrique Romero
Department of Computer Languages and Systems, Universitat Politècnica de Catalunya - BarcelonaTech, Barcelona, Spain
Iván Olier
Institute of Population Health, The University of Manchester, Manchester, United Kingdom
Margarida Julià-Sapé, Carles Arús
Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Cerdanyola del Vallès, Spain
Margarida Julià-Sapé, Carles Arús
Departament de Bioquímica i Biología Molecular, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain
Margarida Julià-Sapé, Carles Arús
Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain
José D. Martín
Departamento de Ingeniería Electrónica, Universidad de Valencia, Burjassot, Spain

Corresponding Author

Email: P.J.Lisboa@ljmu.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SOM HR AV IO ER JM IJ PL. Performed the experiments: SOM IO PL. Analyzed the data: SOM AV IO MJS CA PL. Wrote the paper: SOM AV IO MJS CA PL.