Advertisement
Research Article

No Evidence of Sexual Risk Compensation in the iPrEx Trial of Daily Oral HIV Preexposure Prophylaxis

  • Julia L. Marcus,

    Affiliations: Gladstone Institute of Virology and Immunology, San Francisco, California, United States of America, University of California, Berkeley, California, United States of America

    X
  • David V. Glidden,

    Affiliation: University of California San Francisco, San Francisco, California, United States of America

    X
  • Kenneth H. Mayer,

    Affiliations: Fenway Institute, Fenway Health, Boston, Massachusetts, United States of America, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

    X
  • Albert Y. Liu,

    Affiliations: University of California San Francisco, San Francisco, California, United States of America, Bridge HIV, San Francisco Department of Public Health, San Francisco, California, United States of America

    X
  • Susan P. Buchbinder,

    Affiliations: University of California San Francisco, San Francisco, California, United States of America, Bridge HIV, San Francisco Department of Public Health, San Francisco, California, United States of America

    X
  • K. Rivet Amico,

    Affiliation: Center for Health, Intervention and Prevention, University of Connecticut, Storrs, Connecticut, United States of America

    X
  • Vanessa McMahan,

    Affiliation: Gladstone Institute of Virology and Immunology, San Francisco, California, United States of America

    X
  • Esper Georges Kallas,

    Affiliation: Division of Clinical Immunology and Allergy, School of Medicine, University of São Paulo, São Paulo, Brazil

    X
  • Orlando Montoya-Herrera,

    Affiliation: Fundación Ecuatoriana Equidad, Guayaquil, Guayas, Ecuador

    X
  • Jose Pilotto,

    Affiliation: Laboratorio de AIDS e Imunologia Molecular, Hospital Geral de Nova Iguacu, Rio de Janeiro, Brazil

    X
  • Robert M. Grant mail

    robert.grant@ucsf.edu

    Affiliations: Gladstone Institute of Virology and Immunology, San Francisco, California, United States of America, University of California San Francisco, San Francisco, California, United States of America

    X
  • Published: December 18, 2013
  • DOI: 10.1371/journal.pone.0081997

About the Authors

Julia L. Marcus, Vanessa McMahan, Robert M. Grant
Gladstone Institute of Virology and Immunology, San Francisco, California, United States of America
Julia L. Marcus
University of California, Berkeley, California, United States of America
David V. Glidden, Albert Y. Liu, Susan P. Buchbinder, Robert M. Grant
University of California San Francisco, San Francisco, California, United States of America
Kenneth H. Mayer
Fenway Institute, Fenway Health, Boston, Massachusetts, United States of America
Kenneth H. Mayer
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America
Albert Y. Liu, Susan P. Buchbinder
Bridge HIV, San Francisco Department of Public Health, San Francisco, California, United States of America
K. Rivet Amico
Center for Health, Intervention and Prevention, University of Connecticut, Storrs, Connecticut, United States of America
Esper Georges Kallas
Division of Clinical Immunology and Allergy, School of Medicine, University of São Paulo, São Paulo, Brazil
Orlando Montoya-Herrera
Fundación Ecuatoriana Equidad, Guayaquil, Guayas, Ecuador
Jose Pilotto
Laboratorio de AIDS e Imunologia Molecular, Hospital Geral de Nova Iguacu, Rio de Janeiro, Brazil

Corresponding Author

Email: robert.grant@ucsf.edu

Competing Interests

Co-author Kenneth Mayer has received an unrestricted research grant from Gilead Sciences. Co-author Esper Kallas is a PLOS ONE Editorial Board member. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. For the remaining authors, no conflicts of interest were declared.

Author Contributions

Conceived and designed the experiments: JLM DVG RMG. Analyzed the data: JLM DVG. Wrote the paper: JLM. Coordinated the study: VM. Oversaw the enrollment of participants and procurement of study samples: KHM AYL SPB VM EGK OM JHP. Contributed to the interpretation of the data: KRA KHM AYL SPB VM EGK OM JHP.