Advertisement
Research Article

Distinctive Cytokines as Biomarkers Predicting Fatal Outcome of Severe Staphylococcus aureus Bacteremia in Mice

  • Sanne van den Berg mail,

    s.vandenberg@erasmusmc.nl

    Affiliation: Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre, Rotterdam, The Netherlands

    X
  • Jon D. Laman,

    Affiliation: Department of Immunology, Erasmus University Medical Centre, Rotterdam, The Netherlands

    X
  • Louis Boon,

    Affiliation: Bioceros BV, Utrecht, The Netherlands

    X
  • Marian T. ten Kate,

    Affiliation: Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre, Rotterdam, The Netherlands

    X
  • Gerjo J. de Knegt,

    Affiliation: Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre, Rotterdam, The Netherlands

    X
  • Rob M. Verdijk,

    Affiliation: Department of Pathology, Erasmus University Medical Centre, Rotterdam, The Netherlands

    X
  • Henri A. Verbrugh,

    Affiliation: Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre, Rotterdam, The Netherlands

    X
  • Jan L. Nouwen,

    Affiliation: Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre, Rotterdam, The Netherlands

    X
  • Irma A. J. M. Bakker-Woudenberg

    Affiliation: Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre, Rotterdam, The Netherlands

    X
  • Published: March 08, 2013
  • DOI: 10.1371/journal.pone.0059107

About the Authors

Sanne van den Berg, Marian T. ten Kate, Gerjo J. de Knegt, Henri A. Verbrugh, Jan L. Nouwen, Irma A. J. M. Bakker-Woudenberg
Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre, Rotterdam, The Netherlands
Jon D. Laman
Department of Immunology, Erasmus University Medical Centre, Rotterdam, The Netherlands
Louis Boon
Bioceros BV, Utrecht, The Netherlands
Rob M. Verdijk
Department of Pathology, Erasmus University Medical Centre, Rotterdam, The Netherlands

Corresponding Author

Email: s.vandenberg@erasmusmc.nl

Competing Interests

Louis Boon is employed by Bioceros BV. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. His employment by this company had no influence on this manuscript.

Author Contributions

Conceived and designed the experiments: SvdB JL LB HV JN IBW. Performed the experiments: SvdB MtK GdK RV. Analyzed the data: SvdB JL LB RV JN IBW. Contributed reagents/materials/analysis tools: RV. Wrote the paper: SvdB JL LB RV HV JN IBW.