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Research Article

Restriction of Neural Precursor Ability to Respond to Nurr1 by Early Regional Specification

  • Chiara Soldati,

    Affiliations: Department of Biology and Biotechnology-Neurobiology Research Unit, and “Daniel Bovet” Neurobiology Research Center, “Sapienza” University of Rome, Rome, Italy, “Istituto Pasteur Fondazione Cenci Bolognetti”, Sapienza University of Rome, Rome, Italy

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  • Emanuele Cacci,

    Affiliations: Department of Biology and Biotechnology-Neurobiology Research Unit, and “Daniel Bovet” Neurobiology Research Center, “Sapienza” University of Rome, Rome, Italy, “Istituto Pasteur Fondazione Cenci Bolognetti”, Sapienza University of Rome, Rome, Italy

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  • Stefano Biagioni,

    Affiliation: Department of Biology and Biotechnology-Neurobiology Research Unit, and “Daniel Bovet” Neurobiology Research Center, “Sapienza” University of Rome, Rome, Italy

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  • Nicoletta Carucci,

    Affiliations: Department of Biology and Biotechnology-Neurobiology Research Unit, and “Daniel Bovet” Neurobiology Research Center, “Sapienza” University of Rome, Rome, Italy, “Istituto Pasteur Fondazione Cenci Bolognetti”, Sapienza University of Rome, Rome, Italy

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  • Giuseppe Lupo,

    Affiliations: Department of Biology and Biotechnology-Neurobiology Research Unit, and “Daniel Bovet” Neurobiology Research Center, “Sapienza” University of Rome, Rome, Italy, “Istituto Pasteur Fondazione Cenci Bolognetti”, Sapienza University of Rome, Rome, Italy

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  • Carla Perrone-Capano,

    Affiliations: Department of Biological Sciences, University of Naples Federico II, Naples, Italy, IGB “A. Buzzati Traverso”, Naples, Italy

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  • Isabella Saggio,

    Affiliations: Department of Biology and Biotechnology, “Sapienza” University of Rome, Rome, Italy, “Istituto Pasteur Fondazione Cenci Bolognetti”, “Sapienza” University of Rome, Rome, Italy, Institute of Molecular Biology and Pathology, CNR, Rome, Italy

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  • Gabriella Augusti-Tocco mail

    gabriella.tocco@uniroma1.it

    Affiliation: Department of Biology and Biotechnology-Neurobiology Research Unit, and “Daniel Bovet” Neurobiology Research Center, “Sapienza” University of Rome, Rome, Italy

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  • Published: December 11, 2012
  • DOI: 10.1371/journal.pone.0051798

About the Authors

Chiara Soldati, Emanuele Cacci, Stefano Biagioni, Nicoletta Carucci, Giuseppe Lupo, Gabriella Augusti-Tocco
Department of Biology and Biotechnology-Neurobiology Research Unit, and “Daniel Bovet” Neurobiology Research Center, “Sapienza” University of Rome, Rome, Italy
Chiara Soldati, Emanuele Cacci, Nicoletta Carucci, Giuseppe Lupo
“Istituto Pasteur Fondazione Cenci Bolognetti”, Sapienza University of Rome, Rome, Italy
Carla Perrone-Capano
Department of Biological Sciences, University of Naples Federico II, Naples, Italy
Carla Perrone-Capano
IGB “A. Buzzati Traverso”, Naples, Italy
Isabella Saggio
Department of Biology and Biotechnology, “Sapienza” University of Rome, Rome, Italy
Isabella Saggio
“Istituto Pasteur Fondazione Cenci Bolognetti”, “Sapienza” University of Rome, Rome, Italy
Isabella Saggio
Institute of Molecular Biology and Pathology, CNR, Rome, Italy

Corresponding Author

Email: gabriella.tocco@uniroma1.it

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GAT SB CPC GL. Performed the experiments: CS EC IS NC. Analyzed the data: GAT SB CPC CS EC IS NC. Contributed reagents/materials/analysis tools: GAT SB CPC EC IS GL. Wrote the paper: CS GAT.