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Research Article

Ablation of the Cardiac-Specific Gene Leucine-Rich Repeat Containing 10 (Lrrc10) Results in Dilated Cardiomyopathy

  • Matthew J. Brody,

    Affiliations: Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Molecular and Environmental Toxicology Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Timothy A. Hacker,

    Affiliation: Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Jitandrakumar R. Patel,

    Affiliation: Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Li Feng,

    Affiliation: Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Junichi Sadoshima,

    Affiliation: Department of Cell Biology and Molecular Medicine, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America

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  • Sergei G. Tevosian,

    Affiliation: Department of Physiological Sciences, University of Florida, Gainesville, Florida, United States of America

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  • Ravi C. Balijepalli,

    Affiliation: Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Richard L. Moss,

    Affiliation: Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Youngsook Lee mail

    youngsooklee@wisc.edu

    Affiliations: Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Molecular and Environmental Toxicology Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Published: December 07, 2012
  • DOI: 10.1371/journal.pone.0051621

About the Authors

Matthew J. Brody, Jitandrakumar R. Patel, Richard L. Moss, Youngsook Lee
Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
Matthew J. Brody, Youngsook Lee
Molecular and Environmental Toxicology Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
Timothy A. Hacker, Li Feng, Ravi C. Balijepalli
Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
Junichi Sadoshima
Department of Cell Biology and Molecular Medicine, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
Sergei G. Tevosian
Department of Physiological Sciences, University of Florida, Gainesville, Florida, United States of America

Corresponding Author

Email: youngsooklee@wisc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MJB JS YL. Performed the experiments: MJB TAH JRP LF. Analyzed the data: MJB TAH JRP RCB RLM YL. Contributed reagents/materials/analysis tools: TAH SGT YL. Wrote the paper: MJB YL.