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Research Article

Mice Deficient in Urokinase-Type Plasminogen Activator Have Delayed Healing of Tympanic Membrane Perforations

  • Yue Shen equal contributor,

    equal contributor Contributed equally to this work with: Yue Shen, Yongzhi Guo

    Affiliation: Department of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden

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  • Yongzhi Guo equal contributor,

    equal contributor Contributed equally to this work with: Yue Shen, Yongzhi Guo

    Affiliation: Department of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden

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  • Chun Du,

    Affiliation: Department of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden

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  • Malgorzata Wilczynska,

    Affiliation: Department of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden

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  • Sten Hellström,

    Affiliation: Department of Audiology and Neurotology, Karolinska University Hospital, Stockholm, Sweden

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  • Tor Ny mail

    tor.ny@medchem.umu.se

    Affiliation: Department of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden

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  • Published: December 07, 2012
  • DOI: 10.1371/journal.pone.0051303

About the Authors

Yue Shen, Yongzhi Guo, Chun Du, Malgorzata Wilczynska, Tor Ny
Department of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden
Sten Hellström
Department of Audiology and Neurotology, Karolinska University Hospital, Stockholm, Sweden

Corresponding Author

Email: tor.ny@medchem.umu.se

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YS YG TN. Performed the experiments: YS YG CD. Analyzed the data: YS YG TN. Contributed reagents/materials/analysis tools: TN. Wrote the paper: YS YG MW SH TN.