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Research Article

Effects of a Novel Bradykinin B1 Receptor Antagonist and Angiotensin II Receptor Blockade on Experimental Myocardial Infarction in Rats

  • Dongmei Wu mail,

    dongmeiwu@bellsouth.net

    Affiliations: Department of Research, Mount Sinai Medical Center, Miami Beach, Florida, United States of America, Department of BIN Fusion Technology, WCU program, Chonbuk National University, Jeollabuk-do, Korea

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  • Xinchun Lin,

    Affiliation: Department of Research, Mount Sinai Medical Center, Miami Beach, Florida, United States of America

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  • Christian Bernloehr,

    Affiliation: Boehringer Ingelheim Pharma GmbH & Co.KG, Biberach, Germany

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  • Tobias Hildebrandt,

    Affiliation: Boehringer Ingelheim Pharma GmbH & Co.KG, Biberach, Germany

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  • Henri Doods

    Affiliation: Boehringer Ingelheim Pharma GmbH & Co.KG, Biberach, Germany

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  • Published: December 07, 2012
  • DOI: 10.1371/journal.pone.0051151

About the Authors

Dongmei Wu, Xinchun Lin
Department of Research, Mount Sinai Medical Center, Miami Beach, Florida, United States of America
Dongmei Wu
Department of BIN Fusion Technology, WCU program, Chonbuk National University, Jeollabuk-do, Korea
Christian Bernloehr, Tobias Hildebrandt, Henri Doods
Boehringer Ingelheim Pharma GmbH & Co.KG, Biberach, Germany

Corresponding Author

Email: dongmeiwu@bellsouth.net

Competing Interests

This work was supported by Boehringer Ingelheim Pharma KG, Biberach, Germany; and in part by the World Class University Program (R31-20029) funded by the Ministry of Education, Science and Technology, Republic of Korea. Dr. Wu was a former employee (1996-1999) and consultant of BI and has continued to collaborate with Boehringer Ingelheim Pharma KG. BI-113823 is being developed by Boehringer Ingelheim Pharma. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. This is a collaborative work between Dr. Wu’s laboratory and BI. Christian Bernloehr, Tobias Hildebrandt, and Henri Doods are employed by Boehringer Ingelheim Pharma GmbH & Co.KG. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DW HD. Performed the experiments: XL CB TH. Analyzed the data: DW XL CB TH. Wrote the paper: DW HD.