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Research Article

A Novel Classification of Lung Cancer into Molecular Subtypes

  • Lisandra West equal contributor,

    equal contributor Contributed equally to this work with: Lisandra West, Smruti J. Vidwans, Nicholas P. Campbell

    Affiliation: CollabRx Inc., Palo Alto, California, United States of America

    X
  • Smruti J. Vidwans equal contributor,

    equal contributor Contributed equally to this work with: Lisandra West, Smruti J. Vidwans, Nicholas P. Campbell

    Affiliation: CollabRx Inc., Palo Alto, California, United States of America

    X
  • Nicholas P. Campbell equal contributor,

    equal contributor Contributed equally to this work with: Lisandra West, Smruti J. Vidwans, Nicholas P. Campbell

    Affiliation: Department of Medicine, Section of Hematology/Oncology, The University of Chicago, Chicago, Illinois, United States of America

    X
  • Jeff Shrager,

    Affiliations: CollabRx Inc., Palo Alto, California, United States of America, Symbolic Systems Program (Consulting), Stanford University, Stanford, California, United States of America

    X
  • George R. Simon,

    Affiliation: Department of Medicine, Section of Hematology/Oncology, Medical University of South Carolina, Charleston, South Carolina, United States of America

    X
  • Raphael Bueno,

    Affiliation: Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

    X
  • Phillip A. Dennis,

    Affiliation: National Cancer Institute, Bethesda, Maryland, United States of America

    X
  • Gregory A. Otterson,

    Affiliation: Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America

    X
  • Ravi Salgia mail

    rsalgia@medicine.bsd.uchicago.edu.

    Affiliation: Department of Medicine, Section of Hematology/Oncology, The University of Chicago, Chicago, Illinois, United States of America

    X
  • Published: February 21, 2012
  • DOI: 10.1371/journal.pone.0031906

About the Authors

Lisandra West, Smruti J. Vidwans, Jeff Shrager
CollabRx Inc., Palo Alto, California, United States of America
Nicholas P. Campbell, Ravi Salgia
Department of Medicine, Section of Hematology/Oncology, The University of Chicago, Chicago, Illinois, United States of America
Jeff Shrager
Symbolic Systems Program (Consulting), Stanford University, Stanford, California, United States of America
George R. Simon
Department of Medicine, Section of Hematology/Oncology, Medical University of South Carolina, Charleston, South Carolina, United States of America
Raphael Bueno
Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, Massachusetts, United States of America
Phillip A. Dennis
National Cancer Institute, Bethesda, Maryland, United States of America
Gregory A. Otterson
Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America

Corresponding Author

Email: rsalgia@medicine.bsd.uchicago.edu.

Competing Interests

LEW, SJV, and JS are employees of CollabRx Inc. GO is on the Consulting/Advisory Boards of Genentech and Abraxis/Celgene and receives research funding from Genentech, Pfizer, Boehringer Ingelheim, Tragara, and Abraxis/Celgene. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. RS, NPC, GRS, PAD, and RB have no financial or competing interests to declare.

Author Contributions

Conceived and designed the experiments: LEW SJV NPC RS JS. Performed the experiments: LEW SJV NPC RS JS. Analyzed the data: GRS RB GAO PAD. Contributed reagents/materials/analysis tools: LEW SJV NPC RS JS. Wrote the paper: LEW SJV NPC.