About the Authors
- Keiichi Yamanaka
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* E-mail: yamake@clin.medic.mie-u.ac.jp
Affiliation Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
- Takehisa Nakanishi
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Affiliation Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
- Hiromitsu Saito
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Affiliation Department of Animal Genomics, Functional Genomics Institute, Mie University Life Science Research Center, Tsu, Mie, Japan
- Junko Maruyama
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Affiliation Department of Clinical Engineering, Suzuka University of Medical Science, Suzuka, Mie, Japan
- Kenichi Isoda
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Affiliation Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
- Ayumu Yokochi
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Affiliation Anesthesiology and Critical Care Medicine, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
- Kyoko Imanaka-Yoshida
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Affiliations Pathology and Matrix Biology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan, Mie University Research Center for Matrix Biology, Tsu, Mie, Japan
- Kenshiro Tsuda
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Affiliation Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
- Masato Kakeda
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Affiliation Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
- Ryuji Okamoto
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Affiliation Cardiology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
- Satoshi Fujita
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Affiliation Cardiology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
- Yoichiro Iwakura
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Affiliation Division of Experimental Animal Immunology, Tokyo University of Science, Noda, Chiba, Japan
- Noboru Suzuki
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Affiliation Department of Animal Genomics, Functional Genomics Institute, Mie University Life Science Research Center, Tsu, Mie, Japan
- Masaaki Ito
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Affiliation Cardiology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
- Kazuo Maruyama
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Affiliation Anesthesiology and Critical Care Medicine, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
- Esteban C. Gabazza
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Affiliation Immunology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
- Toshimichi Yoshida
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Affiliations Pathology and Matrix Biology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan, Mie University Research Center for Matrix Biology, Tsu, Mie, Japan
- Motomu Shimaoka
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Affiliation Molecular Pathology and Cell Adhesion Biology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
- Hitoshi Mizutani
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Affiliation Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie, Japan
Competing Interests
Hitoshi Mizutani is an adviser of Oriental Yeast Co., which has commercial interest in the results of this research and technology (KCASP1Tg). The other authors declare no competing financial interests. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: KY ECG TY MS HM. Performed the experiments: KY TN HS JM AY KI KT MK RO SF. Analyzed the data: KY TN HS JM KI AY KI-Y YI NS MI KM. Contributed reagents/materials/analysis tools: KY TN HS JM AY KI-Y KT MK RO SF. Contributed to the writing of the manuscript: KY ECG TY MS HM.