About the Authors

David Köhler

Affiliation Department of Anesthesiology and Intensive Care Medicine, Institute of Experimental and Clinical Pharmacology and Toxicology, Eberhard Karls University Hospitals and Clinics, and Interfaculty Center of Pharmacogenomics and Drug Research, Tuebingen, Germany

Vasudharani Devanathan

Affiliation Department of Pharmacology and Experimental Therapy, Institute of Experimental and Clinical Pharmacology and Toxicology, Eberhard Karls University Hospitals and Clinics, and Interfaculty Center of Pharmacogenomics and Drug Research, Tuebingen, Germany

Claudia Bernardo de Oliveira Franz

Affiliation Department of Anesthesiology and Intensive Care Medicine, Institute of Experimental and Clinical Pharmacology and Toxicology, Eberhard Karls University Hospitals and Clinics, and Interfaculty Center of Pharmacogenomics and Drug Research, Tuebingen, Germany

Therese Eldh

Affiliation Department of Pharmacology and Experimental Therapy, Institute of Experimental and Clinical Pharmacology and Toxicology, Eberhard Karls University Hospitals and Clinics, and Interfaculty Center of Pharmacogenomics and Drug Research, Tuebingen, Germany

Ana Novakovic

Affiliation Department of Pharmacology and Experimental Therapy, Institute of Experimental and Clinical Pharmacology and Toxicology, Eberhard Karls University Hospitals and Clinics, and Interfaculty Center of Pharmacogenomics and Drug Research, Tuebingen, Germany

Judith M. Roth

Affiliation Department of Anesthesiology and Intensive Care Medicine, Institute of Experimental and Clinical Pharmacology and Toxicology, Eberhard Karls University Hospitals and Clinics, and Interfaculty Center of Pharmacogenomics and Drug Research, Tuebingen, Germany

Tiago Granja

Affiliation Department of Anesthesiology and Intensive Care Medicine, Institute of Experimental and Clinical Pharmacology and Toxicology, Eberhard Karls University Hospitals and Clinics, and Interfaculty Center of Pharmacogenomics and Drug Research, Tuebingen, Germany

Lutz Birnbaumer

Affiliation Laboratory of Neurobiology, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, United States of America

Peter Rosenberger

Affiliation Department of Anesthesiology and Intensive Care Medicine, Institute of Experimental and Clinical Pharmacology and Toxicology, Eberhard Karls University Hospitals and Clinics, and Interfaculty Center of Pharmacogenomics and Drug Research, Tuebingen, Germany

Sandra Beer-Hammer

sandra.beer-hammer@uni-tuebingen.de (SBH); bernd.nuernberg@uni-tuebingen.de (BN)

Affiliation Department of Pharmacology and Experimental Therapy, Institute of Experimental and Clinical Pharmacology and Toxicology, Eberhard Karls University Hospitals and Clinics, and Interfaculty Center of Pharmacogenomics and Drug Research, Tuebingen, Germany

Bernd Nürnberg

sandra.beer-hammer@uni-tuebingen.de (SBH); bernd.nuernberg@uni-tuebingen.de (BN)

Affiliation Department of Pharmacology and Experimental Therapy, Institute of Experimental and Clinical Pharmacology and Toxicology, Eberhard Karls University Hospitals and Clinics, and Interfaculty Center of Pharmacogenomics and Drug Research, Tuebingen, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DK VD CB LB PR SBH BN. Performed the experiments: DK VD CB TE AN JR TG. Analyzed the data: DK VD TG SBH. Contributed reagents/materials/analysis tools: LB PR BN. Wrote the paper: DK VD TE SBH BN.