About the Authors

Min Zhu

Contributed equally to this work with: Min Zhu, Mingyang Li, Fan Zhang, Fan Feng

Affiliation Department of oncology, Nan Lou Division, Chinese PLA General Hospital, Beijing, P. R. China

Mingyang Li

Contributed equally to this work with: Min Zhu, Mingyang Li, Fan Zhang, Fan Feng

Affiliation Department of Gastroenterology, Nan Lou Division, Chinese PLA General Hospital, Beijing, P. R. China

Fan Zhang

Contributed equally to this work with: Min Zhu, Mingyang Li, Fan Zhang, Fan Feng

Affiliation Tumor Center, Chinese PLA General Hospital, Beijing, P. R. China

Fan Feng

Contributed equally to this work with: Min Zhu, Mingyang Li, Fan Zhang, Fan Feng

Affiliation Department of Pharmacy, General Hospital of Shenyang Military Command, Shenyang, P. R. China

Weihao Chen

Affiliation Department of Urology, Chinese PLA General Hospital, Beijing, P. R. China

Yutao Yang

Affiliation Beijing Institute for Neuroscience, Capital Medical University, Beijing, P. R. China

Jiajun Cui

Affiliation Department of Cancer and cell Biology, College of Medicine, University of Cincinnati, Cincinnati, Ohio, United States of America

Dong Zhang

zhangd1117@yahoo.com (DZ); 13341088278@126.com (EL)

Affiliation Department of oncology, Nan Lou Division, Chinese PLA General Hospital, Beijing, P. R. China

Enqiang Linghu

zhangd1117@yahoo.com (DZ); 13341088278@126.com (EL)

Affiliation Department of Gastroenterology, Chinese PLA General Hospital, Beijing, P. R. China

Competing Interests

Roche's Scientific Corporation Program provided funding towards this study. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: FF JC DZ EL. Performed the experiments: MZ ML YY. Analyzed the data: FZ. Contributed reagents/materials/analysis tools: WC. Wrote the paper: FF. Provided some important plasmids in this work: JC. Retouched and polished the manuscript and response letter in the process of revision: JC.