About the Authors

Yuet-Kin Leung

Contributed equally to this work with: Yuet-Kin Leung, Queeny Kwan-Yi Chan

Affiliation Department of Environmental Health, Center for Environmental Genetics, and Cancer Institute, University of Cincinnati Medical Center, Cincinnati, Ohio, United States of America

Queeny Kwan-Yi Chan

Contributed equally to this work with: Yuet-Kin Leung, Queeny Kwan-Yi Chan

Affiliation Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

Chi-Fai Ng

Affiliation Department of Surgery, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

Fanny Man-Ting Ma

Affiliation Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

Ho-Man Tse

Affiliation Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

Ka-Fai To

Affiliations Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China, State Key Laboratory in Southern China in Oncology, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

Jodi Maranchie

Affiliation Department of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Shuk-Mei Ho

hosm@uc.edu (SMH); kmlau@cuhk.edu.hk (KML)

Affiliations Department of Environmental Health, Center for Environmental Genetics, and Cancer Institute, University of Cincinnati Medical Center, Cincinnati, Ohio, United States of America, Cincinnati Veteran Affairs Medical Center, Cincinnati, Ohio, United States of America

Kin-Mang Lau

hosm@uc.edu (SMH); kmlau@cuhk.edu.hk (KML)

Affiliations Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China, State Key Laboratory in Southern China in Oncology, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

Competing Interests

Dr. Jodi Maranchie received the Investigator-Sponsored Study Program of AstraZeneca. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: YKL QKYC CFN FMTM HMT KFT JM SMH KML. Performed the experiments: YKL QKYC CFN FMTM HMT. Analyzed the data: YKL QKYC CFN FMTM HMT KFT JM SMH KML. Contributed reagents/materials/analysis tools: KFT JM SMH KML. Wrote the paper: YKL QKYC JM SMH KML.