About the Authors

Adrian Gheorghe

Affiliation Primary Care Clinical Sciences, University of Birmingham, Birmingham, United Kingdom

Tracy E. Roberts

Affiliation Health Economics Unit, University of Birmingham, Birmingham, United Kingdom

Thomas D. Pinkney

Affiliations Academic Department of Surgery, University of Birmingham, Birmingham, United Kingdom, West Midlands Research Collaborative, Birmingham, United Kingdom

David C. Bartlett

Affiliation West Midlands Research Collaborative, Birmingham, United Kingdom

Dion Morton

Affiliations Academic Department of Surgery, University of Birmingham, Birmingham, United Kingdom, West Midlands Research Collaborative, Birmingham, United Kingdom

Melanie Calvert

m.calvert@bham.ac.uk

Affiliations Primary Care Clinical Sciences, University of Birmingham, Birmingham, United Kingdom, West Midlands Research Collaborative, Birmingham, United Kingdom

on behalf of the West Midlands Research Collaborative and the ROSSINI Trial Investigators

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TP MC DB DM. Performed the experiments: TP MC DB DM. Analyzed the data: AG MC TR TP DB. Contributed reagents/materials/analysis tools: AG MC TR TP DB. Wrote the paper: AG MC TR TP DB DM.