About the Authors

Sheng Wen

Affiliation Stem Cell Biology and Therapy Laboratory of Ministry of Education Key Laboratory for Pediatrics, Chongqing Stem Cell Therapy and Engineering Center, and Department of Urology, The Children's Hospital of Chongqing Medical University, Chongqing, China

Hongmei Zhang

Affiliations Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, and the Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, China, Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America

Yasha Li

Affiliation Stem Cell Biology and Therapy Laboratory of Ministry of Education Key Laboratory for Pediatrics, Chongqing Stem Cell Therapy and Engineering Center, and Department of Urology, The Children's Hospital of Chongqing Medical University, Chongqing, China

Ning Wang

Affiliations Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America, Departments of Cell Biology and Oncology of the Affiliated Southwest Hospital, the Third Military Medical University, Chongqing, China

Wenwen Zhang

Affiliations Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America, Ministry of Education Key Laboratory of Diagnostic Medicine and School of Clinical Diagnostic Medicine, and the Affiliated Hospitals, Chongqing Medical University, Chongqing, China

Ke Yang

Affiliations Stem Cell Biology and Therapy Laboratory of Ministry of Education Key Laboratory for Pediatrics, Chongqing Stem Cell Therapy and Engineering Center, and Department of Urology, The Children's Hospital of Chongqing Medical University, Chongqing, China, Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America

Ningning Wu

Affiliations Stem Cell Biology and Therapy Laboratory of Ministry of Education Key Laboratory for Pediatrics, Chongqing Stem Cell Therapy and Engineering Center, and Department of Urology, The Children's Hospital of Chongqing Medical University, Chongqing, China, Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America, Ministry of Education Key Laboratory of Diagnostic Medicine and School of Clinical Diagnostic Medicine, and the Affiliated Hospitals, Chongqing Medical University, Chongqing, China

Xian Chen

Affiliations Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America, Ministry of Education Key Laboratory of Diagnostic Medicine and School of Clinical Diagnostic Medicine, and the Affiliated Hospitals, Chongqing Medical University, Chongqing, China

Fang Deng

Affiliations Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America, Departments of Cell Biology and Oncology of the Affiliated Southwest Hospital, the Third Military Medical University, Chongqing, China

Zhan Liao

Affiliations Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America, Department of Orthopaedic Surgery, the Affiliated Xiang-Ya Hospital of Central South University, Changsha, China

Junhui Zhang

Affiliations Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America, Ministry of Education Key Laboratory of Diagnostic Medicine and School of Clinical Diagnostic Medicine, and the Affiliated Hospitals, Chongqing Medical University, Chongqing, China

Qian Zhang

Affiliations Stem Cell Biology and Therapy Laboratory of Ministry of Education Key Laboratory for Pediatrics, Chongqing Stem Cell Therapy and Engineering Center, and Department of Urology, The Children's Hospital of Chongqing Medical University, Chongqing, China, Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America

Zhengjian Yan

Affiliations Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America, Ministry of Education Key Laboratory of Diagnostic Medicine and School of Clinical Diagnostic Medicine, and the Affiliated Hospitals, Chongqing Medical University, Chongqing, China

Wei Liu

Affiliations Stem Cell Biology and Therapy Laboratory of Ministry of Education Key Laboratory for Pediatrics, Chongqing Stem Cell Therapy and Engineering Center, and Department of Urology, The Children's Hospital of Chongqing Medical University, Chongqing, China, Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America

Zhonglin Zhang

Affiliations Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America, Department of Surgery, the Affiliated Zhongnan Hospital of Wuhan University, Wuhan, China

Jixing Ye

Affiliations Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America, School of Bioengineering, Chongqing University, Chongqing, China

Youlin Deng

Affiliations Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America, Ministry of Education Key Laboratory of Diagnostic Medicine and School of Clinical Diagnostic Medicine, and the Affiliated Hospitals, Chongqing Medical University, Chongqing, China

Guolin Zhou

Affiliation Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America

Hue H. Luu

Affiliation Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America

Rex C. Haydon

Affiliation Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America

Lewis L. Shi

Affiliation Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, Illinois, United States of America

Tong-Chuan He

tche@uchicago.edu (TCH); guanghuiwei2012@gmail.com (GW)

Affiliations Stem Cell Biology and Therapy Laboratory of Ministry of Education Key Laboratory for Pediatrics, Chongqing Stem Cell Therapy and Engineering Center, and Department of Urology, The Children's Hospital of Chongqing Medical University, Chongqing, China, Ministry of Education Key Laboratory of Diagnostic Medicine and School of Clinical Diagnostic Medicine, and the Affiliated Hospitals, Chongqing Medical University, Chongqing, China

Guanghui Wei

tche@uchicago.edu (TCH); guanghuiwei2012@gmail.com (GW)

Affiliation Stem Cell Biology and Therapy Laboratory of Ministry of Education Key Laboratory for Pediatrics, Chongqing Stem Cell Therapy and Engineering Center, and Department of Urology, The Children's Hospital of Chongqing Medical University, Chongqing, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TCH GW LLS RCH LLH SW. Performed the experiments: SW HZ N. Wang WZ N. Wu XC FD. Analyzed the data: SW GZ ZL TCH. Contributed reagents/materials/analysis tools: YL KY JZ QZ ZY WL ZZ JY YD. Wrote the paper: TCH GW SW LLS RCH HHL.