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Research Article

Stem and Progenitor Cell Subsets Are Affected by JAK2 Signaling and Can Be Monitored by Flow Cytometry

  • Ryuji Iida,

    Affiliation: Immunobiology and Cancer Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America

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  • Robert S. Welner,

    Affiliation: Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

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  • Wanke Zhao,

    Affiliation: Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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  • José Alberola-lla,

    Affiliation: Immunobiology and Cancer Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America

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  • Kay L. Medina,

    Affiliation: Department of Immunology, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Zhizhuang Joe Zhao,

    Affiliation: Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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  • Paul W. Kincade mail

    kincade@omrf.org

    Affiliation: Immunobiology and Cancer Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America

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  • Published: April 03, 2014
  • DOI: 10.1371/journal.pone.0093643

About the Authors

Ryuji Iida, José Alberola-lla, Paul W. Kincade
Immunobiology and Cancer Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America
Robert S. Welner
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America
Wanke Zhao, Zhizhuang Joe Zhao
Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
Kay L. Medina
Department of Immunology, Mayo Clinic, Rochester, Minnesota, United States of America

Corresponding Author

Email: kincade@omrf.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RI RSW JAI KLM ZJZ PWK. Performed the experiments: RI RSW WZ. Analyzed the data: RI RSW ZJZ PWK. Contributed reagents/materials/analysis tools: ZJZ PWK. Wrote the paper: RI RSW ZJZ PWK.