About the Authors

Stefanie Lerche

Stefanie.lerche@uni-tuebingen.de

Affiliations Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany, German Center for Neurodegenerative Diseases, University of Tübingen, Tübingen, Germany

Markus Hobert

Affiliations Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany, German Center for Neurodegenerative Diseases, University of Tübingen, Tübingen, Germany

Kathrin Brockmann

Affiliations Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany, German Center for Neurodegenerative Diseases, University of Tübingen, Tübingen, Germany

Isabel Wurster

Affiliations Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany, German Center for Neurodegenerative Diseases, University of Tübingen, Tübingen, Germany

Alexandra Gaenslen

Affiliations Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany, German Center for Neurodegenerative Diseases, University of Tübingen, Tübingen, Germany

Sandra Hasmann

Affiliations Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany, German Center for Neurodegenerative Diseases, University of Tübingen, Tübingen, Germany

Gerhard W. Eschweiler

Affiliation Geriatric Center and Department of Psychiatry and Psychotherapy, University Hospital of Tübingen, Tübingen, Germany

Walter Maetzler

Affiliations Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany, German Center for Neurodegenerative Diseases, University of Tübingen, Tübingen, Germany

Daniela Berg

Affiliations Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany, German Center for Neurodegenerative Diseases, University of Tübingen, Tübingen, Germany

Competing Interests

Dr. Lerche, Mr. Hobert, Ms. Wurster, Dr. Gaenslen and Ms. Hasmann reports no disclosures. Dr. Brockmann has received honoraria for lectures from the Deutsche Gesellschaft für klinische Neurophysiologie (DGKN) as well as travel grants from GlaxoSmithKline, UCB and the Movement Disorders Society. Prof. Maetzler has received speaker honoraria from GlaxoSmithKline, and receives research support from the European Union and the Robert Bosch Foundation. Prof. Eschweiler has received grants for Phase II and phase III study in alzheimer disorders from AC Immune and Janssen Alzheimer Immunotherapy Research. Prof. Berg has received Advisory Boards from UCB SchwarzPharma, Novartis, Merz; Honoraria from UCB SchwarzPharma, GSK, TEVA, Lundbeck; Grants from Michael J Fox Foundation, BmBF, Janssen Pharmaceutica, TEVA Pharma GmbH, Böhringer, dPV (German Parkinson's disease association), Abbott and Center of Integrative Neurosciences. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SL DB GE. Performed the experiments: MH KB IW AG SH. Analyzed the data: SL WM DB. Contributed reagents/materials/analysis tools: WM GE DB. Wrote the paper: SL. Critical revision of the manuscript for important intellectual content: MH KB IW AG SH WM GE DB. Statistical analysis: SL. Obtained funding: DB. Study supervision: GE DB.