About the Authors

Vinícius Silva Machado

Affiliation Department of Population Medicine & Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Marcela Luccas de Souza Bicalho

Affiliation Department of Population Medicine & Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Enoch Brandão de Souza Meira Junior

Affiliation Department of Population Medicine & Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Rodolfo Rossi

Affiliation Department of Population Medicine & Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Bruno Leonardo Ribeiro

Affiliation Department of Population Medicine & Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Svetlana Lima

Affiliation Department of Population Medicine & Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Thiago Santos

Affiliation Department of Population Medicine & Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Arieli Kussler

Affiliation Department of Population Medicine & Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Carla Foditsch

Affiliation Department of Population Medicine & Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Erika Korzune Ganda

Affiliation Department of Population Medicine & Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Georgios Oikonomou

Affiliation Department of Population Medicine & Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Soon Hon Cheong

Affiliation Department of Population Medicine & Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Robert Owen Gilbert

Affiliation Department of Population Medicine & Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Rodrigo Carvalho Bicalho

rcb28@cornell.edu

Affiliation Department of Population Medicine & Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Competing Interests

Rodrigo Carvalho Bicalho, Robert Owen Gilbert, Marcela Luccas de Souza Bicalho, and Vinicius Silva Machado have a pending patent entitled “Vaccine for the prevention of uterine diseases” (Application number 61/731,333) on the vaccine technology described in this manuscript. This study was funded by Merck Animal Health. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RCB VSM ROG SHC. Performed the experiments: VSM MLdSB EBdSM RR BLR SL TS AK CF EKG. Analyzed the data: RCB VSM. Contributed reagents/materials/analysis tools: RCB. Wrote the paper: VSM RCB GO.