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Research Article

Cell-SELEX Aptamer for Highly Specific Radionuclide Molecular Imaging of Glioblastoma In Vivo

  • Xidong Wu equal contributor,

    equal contributor Contributed equally to this work with: Xidong Wu, Huiyu Liang

    Affiliation: Department of Neurobiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China

    X
  • Huiyu Liang equal contributor,

    equal contributor Contributed equally to this work with: Xidong Wu, Huiyu Liang

    Affiliation: Department of Neurobiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China

    X
  • Yan Tan,

    Affiliation: Department of Neurobiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China

    X
  • Chao Yuan,

    Affiliation: Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China

    X
  • Shuji Li,

    Affiliation: Department of Neurobiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China

    X
  • Xiaowen Li,

    Affiliation: Department of Neurobiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China

    X
  • Guiping Li,

    Affiliation: Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China

    X
  • Yusheng Shi mail,

    zxmray@hotmail.com (XZ); 390637670@qq.com (YS)

    Affiliation: Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China

    X
  • Xingmei Zhang mail

    zxmray@hotmail.com (XZ); 390637670@qq.com (YS)

    Affiliation: Department of Neurobiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China

    X
  • Published: March 06, 2014
  • DOI: 10.1371/journal.pone.0090752

About the Authors

Xidong Wu, Huiyu Liang, Yan Tan, Shuji Li, Xiaowen Li, Xingmei Zhang
Department of Neurobiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China
Chao Yuan
Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China
Guiping Li
Department of Nuclear Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China
Yusheng Shi
Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XZ YS. Performed the experiments: XW HL YT. Analyzed the data: XW HL. Contributed reagents/materials/analysis tools: CY SL XL GL. Wrote the paper: XW HL.