About the Authors

Jonathan Z. Li

Jli22@partners.org

Affiliation Division of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Brad Chapman

Affiliation Harvard School of Public Health, Boston, Massachusetts, United States of America

Patrick Charlebois

Affiliation Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Oliver Hofmann

Affiliation Harvard School of Public Health, Boston, Massachusetts, United States of America

Brian Weiner

Affiliation Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Alyssa J. Porter

Affiliation Harvard School of Public Health, Boston, Massachusetts, United States of America

Reshmi Samuel

Affiliations Division of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Virology, University of KwaZulu-Natal, National Health Laboratory Service, Durban, South Africa

Saran Vardhanabhuti

Affiliation Harvard School of Public Health, Boston, Massachusetts, United States of America

Lu Zheng

Affiliation Harvard School of Public Health, Boston, Massachusetts, United States of America

Joseph Eron

Affiliation Division of Infectious Diseases, University of North Carolina, Chapel Hill, North Carolina, United States of America

Babafemi Taiwo

Affiliation Division of Infectious Diseases, Northwestern University, Chicago, Illinois, United States of America

Michael C. Zody

Affiliation Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Matthew R. Henn

Affiliation Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Daniel R. Kuritzkes

Affiliation Division of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Winston Hide

Affiliation Harvard School of Public Health, Boston, Massachusetts, United States of America

and the ACTG A5262 Study Team

Membership of the ACTG A5262 Study Team is provided in the Acknowledgments.

Competing Interests

Dr. Li has served as a consultant for Therapy Edge, Quest Diagnostics, and SeraCare Life Sciences. Dr. Kuritzkes has served as a consultant to and/or has received research grant support from Abbott, Avexa, Bristol-Myers Squibb, Boehringer-Ingelheim, Gilead, GlaxoSmithKline, Merck, Roche, Tobira, Vertex, ViroStatistics, and ViiV Healthcare; he has also received speaking honoraria from Gilead and Roche. No other potential conflicts of interest relevant to this article were reported.

Author Contributions

Conceived and designed the experiments: JZL BC OH RS MH WH DRK. Performed the experiments: JZL BC PC OH BW AJP RS MZ MH WH DRK. Analyzed the data: JZL BC PC OH BW SV LZ MZ MH WH DRK. Contributed reagents/materials/analysis tools: JE BT. Wrote the paper: JZL BC OH WH DRK.