About the Authors

Roland Faigle

Affiliation Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Anjail Sharrief

Affiliations Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Neurology, University of Texas Health Science Center, Houston, Texas, United States of America

Elisabeth B. Marsh

Affiliation Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Rafael H. Llinas

Affiliation Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Victor C. Urrutia

vurruti1@jhmi.edu

Affiliation Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Competing Interests

Victor C. Urrutia has read the journal's policy and has the following conflicts: 1. PI for the investigator initiated trial SAIL ON (a pilot clinical trial of IV tPA treatment for patients that wake up with stroke). Genentec Inc. has provided funding for this trial. 2. PI at Johns Hopkins for the multicenter clinical trial DIAS 4. Sponsor is Lundbeck. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: VCU RF AS. Performed the experiments: RF AS. Analyzed the data: VCU RF AS. Contributed reagents/materials/analysis tools: VCU RHL EBM. Wrote the paper: RF VCU EBM RHL.