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Research Article

Cultivation of Corneal Endothelial Cells on a Pericellular Matrix Prepared from Human Decidua-Derived Mesenchymal Cells

  • Ryohei Numata,

    Affiliation: Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan

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  • Naoki Okumura,

    Affiliations: Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan, Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan

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  • Makiko Nakahara,

    Affiliation: Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan

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  • Morio Ueno,

    Affiliation: Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan

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  • Shigeru Kinoshita,

    Affiliation: Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan

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  • Daisuke Kanematsu,

    Affiliation: Division of Regenerative Medicine, Institute for Clinical Research, Osaka National Hospital, National Hospital Organization, Osaka, Japan

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  • Yonehiro Kanemura,

    Affiliation: Division of Regenerative Medicine, Institute for Clinical Research, Osaka National Hospital, National Hospital Organization, Osaka, Japan

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  • Yoshiki Sasai,

    Affiliation: RIKEN Center for Developmental Biology, Hyogo, Japan

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  • Noriko Koizumi mail

    nkoizumi@mail.doshisha.ac.jp

    Affiliation: Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan

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  • Published: February 05, 2014
  • DOI: 10.1371/journal.pone.0088169

About the Authors

Ryohei Numata, Naoki Okumura, Makiko Nakahara, Noriko Koizumi
Department of Biomedical Engineering, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan
Naoki Okumura, Morio Ueno, Shigeru Kinoshita
Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
Daisuke Kanematsu, Yonehiro Kanemura
Division of Regenerative Medicine, Institute for Clinical Research, Osaka National Hospital, National Hospital Organization, Osaka, Japan
Yoshiki Sasai
RIKEN Center for Developmental Biology, Hyogo, Japan

Corresponding Author

Email: nkoizumi@mail.doshisha.ac.jp

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NO MU SK YS NK. Performed the experiments: RN MN. Analyzed the data: RN MN NO NK. Contributed reagents/materials/analysis tools: SK DK YK YS NK. Wrote the paper: NO NK.